HitPredict

Interactor 1: ESM7 (P13097)
Enhancer of split m7 protein (E(spl)m7)
Gene: E(spl)m7-HLH

Interactor 2: ATO (P48987)
Protein atonal
Gene: ATO

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.43	1.00	0.656

Property	Details
Experiments	9371806
Identification Methods	two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	HLH~HLH
Common GO terms	GO:0005634 - nucleus GO:0007399 - nervous system development
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 186 Dm			1 312
+	Dm
		878206 ESMB_DROME (1-186): 8e-53: 168: 44.06		ATO_DROME (1-312): 1.08e-146: 416: 100.00
+	Dm
		560204 ESM8_DROME (7-186): 1.08e-51: 165: 40.00		ATO_DROME (1-312): 1.08e-146: 416: 100.00
+	Dm
		878205 ESM3_DROME (3-186): 1.05e-44: 149: 35.56		ATO_DROME (1-312): 1.08e-146: 416: 100.00
+	Dm
		542894 ESM7_DROME (1-186): 1.5e-64: 198: 100.00		DA_DROME (132-312): 3.71e-25: 107: 19.67
+	Dm
		195841 ESMB_DROME (1-186): 8e-53: 168: 44.06		TAP_DROME (147-312): 4.4e-30: 119: 25.00
+	Dm
		542908 ESMB_DROME (1-186): 8e-53: 168: 44.06		DA_DROME (132-312): 3.71e-25: 107: 19.67
+	Dm
		542895 ESM8_DROME (7-186): 1.08e-51: 165: 40.00		DA_DROME (132-312): 3.71e-25: 107: 19.67
+	Dm
		542909 ESMC_DROME (6-186): 2.49e-51: 165: 47.48		DA_DROME (132-312): 3.71e-25: 107: 19.67
+	Dm
		195838 ESM5_DROME (8-186): 3.81e-43: 143: 40.00		TAP_DROME (147-312): 4.4e-30: 119: 25.00
+	Dm
		1175926 DPN_DROME (9-181): 1.57e-43: 151: 26.82		Q86PA6_DROME (132-312): 2.35e-25: 108: 19.67
+	Dm
		542912 DPN_DROME (9-181): 1.57e-43: 151: 26.82		DA_DROME (132-312): 3.71e-25: 107: 19.67
+	Hs
		1037913 HES1_HUMAN (3-123): 6.04e-44: 148: 35.43		HEN2_HUMAN (199-311): 1.01e-28: 109: 29.69
+	Hs
		1108879 HEY1_HUMAN (7-180): 5.83e-44: 149: 22.40		OLIG2_HUMAN (163-312): 1.07e-25: 106: 26.58
+	Mm
		1222212 HEYL_MOUSE (9-185): 2.06e-44: 151: 25.13		HAND2_MOUSE (202-311): 2.02e-25: 103: 29.09
+	Mm
		1222213 HEY2_MOUSE (7-182): 1.87e-43: 149: 23.90		HAND2_MOUSE (202-311): 2.02e-25: 103: 29.09
+	Mm
		1222214 HEY1_MOUSE (7-180): 6.97e-44: 149: 22.40		HAND2_MOUSE (202-311): 2.02e-25: 103: 29.09
+	Dm
		542893 ESM5_DROME (8-186): 3.81e-43: 143: 40.00		DA_DROME (132-312): 3.71e-25: 107: 19.67
+	Hs
		1393916 HES6_HUMAN (9-186): 6.98e-39: 134: 28.50		NGN3_HUMAN (168-312): 2.72e-28: 110: 27.59
+	Hs
		154934 BHE40_HUMAN (6-181): 2.69e-37: 134: 22.44		TFE2_HUMAN (127-312): 7.34e-26: 109: 20.86
+	Mm
		586149 BHE41_MOUSE (5-181): 4.78e-37: 134: 23.98		TFE2_MOUSE (134-312): 1.92e-25: 108: 22.22