Interactor 1: GFAP (P14136)
Glial fibrillary acidic protein (GFAP)
Gene: GFAP
Interactor 2: DESM (P17661)
Desmin
Gene: DES
Species: Homo sapiens
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.89 | 1.00 | 0.948 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 28514442, 32296183, 34079125, 33961781, 32814053, unassigned1304 |
| Identification Methods | affinity chromatography technology, two hybrid, proximity labelling technology, validated two hybrid, anti tag coimmunoprecipitation, two hybrid prey pooling approach, two hybrid array, two hybrid pooling approach |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Filament~Filament |
| Common GO terms | GO:0005200 - structural constituent of cytoskeleton GO:0005829 - cytosol GO:0005882 - intermediate filament GO:0045109 - intermediate filament organization GO:0045111 - intermediate filament cytoskeleton |
| Homologous interactions | 19 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
