Interactor 1: HLAG (P17693)
HLA class I histocompatibility antigen, alpha chain G (HLA G antigen) (MHC class I antigen G) [Cleaved into: Soluble HLA class I histocompatibility antigen, alpha chain G (sHLA-G)]
Gene: HLA-G

Interactor 2: KI2L4 (Q99706)
Killer cell immunoglobulin-like receptor 2DL4 (CD158 antigen-like family member D) (G9P) (Killer cell inhibitory receptor 103AS) (KIR-103AS) (MHC class I NK cell receptor KIR103AS) (CD antigen CD158d)
Gene: KIR2DL4

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.58 1.00 0.768

The method score is based on:

Property Details
Experiments 10190900, 16487070
Identification Methods pull down
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains C1-set~ig, MHC_I~ig
Common GO terms GO:0002729 - positive regulation of natural killer cell cytokine production
GO:0005886 - plasma membrane
GO:0006968 - cellular defense response
GO:0016020 - membrane
GO:0031901 - early endosome membrane
and 2 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 338
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024