HitPredict

Interactor 1: IL2RB (P14784)
Interleukin-2 receptor subunit beta (IL-2 receptor subunit beta) (IL-2R subunit beta) (IL-2RB) (High affinity IL-2 receptor subunit beta) (Interleukin-15 receptor subunit beta) (p70-75) (p75) (CD antigen CD122)
Gene: IL2RB

Interactor 2: STAT1 (P42224)
Signal transducer and activator of transcription 1-alpha/beta (Transcription factor ISGF-3 components p91/p84)
Gene: STAT1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	10602027
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 551 Hs			1 750
+	Hs
		575813 IL2RB_HUMAN (1-551): 0: 527: 100.00		STAT3_HUMAN (1-740): 0: 864: 52.61
+	Hs
		575827 IL2RB_HUMAN (1-551): 0: 527: 100.00		STAT4_HUMAN (1-749): 0: 854: 52.65
+	Hs
		575819 IL2RB_HUMAN (1-551): 0: 527: 100.00		STA5B_HUMAN (1-749): 0: 787: 28.82
+	Hs
		575816 IL2RB_HUMAN (1-551): 0: 527: 100.00		STA5A_HUMAN (1-748): 0: 780: 28.14
+	Mm
		593805 IL2RB_MOUSE (1-551): 3.92e-167: 486: 56.84		STA5A_MOUSE (1-748): 0: 793: 27.79
+	Mm
		593806 IL2RB_MOUSE (1-551): 3.92e-167: 486: 56.84		STA5B_MOUSE (1-748): 0: 782: 28.13
+	Hs
		599174 IL7RA_HUMAN (92-351): 4.7e-52: 185: 16.60		STAT1_HUMAN (1-750): 0: 988: 100.00
+	Hs
		838095 I13R2_HUMAN (26-261): 2.56e-51: 182: 13.75		STAT1_HUMAN (1-750): 0: 988: 100.00
+	Hs
		533835 GHR_HUMAN (7-485): 4.74e-75: 252: 16.57		STAT3_HUMAN (1-740): 0: 864: 52.61
+	Mm
		838404 PRLR_MOUSE (6-456): 1.04e-96: 308: 14.22		STA5A_MOUSE (1-748): 0: 793: 27.79
+	Mm
		599253 GHR_MOUSE (22-522): 1.42e-61: 215: 14.69		STAT3_MOUSE (1-740): 0: 865: 52.61
+	Hs
		599170 IL7RA_HUMAN (92-351): 4.7e-52: 185: 16.60		STAT3_HUMAN (1-740): 0: 864: 52.61
+	Mm
		594822 IL4RA_MOUSE (1-521): 5.82e-47: 177: 16.94		STAT3_MOUSE (1-740): 0: 865: 52.61
+	Hs
		533838 GHR_HUMAN (7-485): 4.74e-75: 252: 16.57		STA5B_HUMAN (1-749): 0: 787: 28.82
+	Hs
		596943 PRLR_HUMAN (24-547): 4.86e-75: 251: 12.96		STA5B_HUMAN (1-749): 0: 787: 28.82
+	Mm
		599254 GHR_MOUSE (22-522): 1.42e-61: 215: 14.69		STA5A_MOUSE (1-748): 0: 793: 27.79
+	Mm
		599255 GHR_MOUSE (22-522): 1.42e-61: 215: 14.69		STA5B_MOUSE (1-748): 0: 782: 28.13
+	Hs
		619211 EPOR_HUMAN (7-446): 3.18e-60: 209: 18.49		STA5A_HUMAN (1-748): 0: 780: 28.14
+	Hs
		599175 IL7RA_HUMAN (92-351): 4.7e-52: 185: 16.60		STA5A_HUMAN (1-748): 0: 780: 28.14
+	Mm
		594823 IL4RA_MOUSE (1-521): 5.82e-47: 177: 16.94		STAT6_MOUSE (1-747): 0: 634: 26.46