Protein: EPOR
Erythropoietin receptor (EPO-R)

Gene: EPOR
Organism: Homo sapiens
Interactions: 45
UniProt ID: P19235

Gene Ontology (top 5):
GO:0004900 - erythropoietin receptor activity
GO:0005576 - extracellular region
GO:0005886 - plasma membrane
GO:0007165 - signal transduction
GO:0007420 - brain development

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

619230

CISH
Cytokine-inducible SH2-containing protein

6

20

Small-scale

0.935

High

378589

EPO
Erythropoietin

10

0

Small-scale

0.927

High

619207

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

5

11

Small-scale

0.920

High

619208

PTN6
Tyrosine-protein phosphatase non-receptor type 6

4

20

Small-scale

0.904

High

155075

SOCS2
Suppressor of cytokine signaling 2

4

20

Small-scale

0.898

High

253294

JAK2
Tyrosine-protein kinase JAK2

3

20

Small-scale

0.861

High

619211

STA5A
Signal transducer and activator of transcription 5A

3

20

Small-scale

0.861

High

619213

CRKL
Crk-like protein

3

20

Small-scale

0.857

High

619214

GRB2
Growth factor receptor-bound protein 2

3

20

Small-scale

0.849

High

155905

SOCS3
Suppressor of cytokine signaling 3

2

20

Small-scale

0.817

High

619228

SHIP1
Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1

2

2

Small-scale

0.786

High

619218

PTN11
Tyrosine-protein phosphatase non-receptor type 11

2

20

Small-scale

0.768

High

463323

LYN
Tyrosine-protein kinase Lyn

1

18

Small-scale

0.724

High

619220

GRAP
GRB2-related adapter protein

1

20

Small-scale

0.681

High

154419

SH2B2
SH2B adapter protein 2

1

20

Small-scale

0.647

High

619203

EPOR
Erythropoietin receptor

1

17

Small-scale

0.647

High

610975

PTN1
Tyrosine-protein phosphatase non-receptor type 1

1

20

Small-scale

0.640

High

618967

PLCG1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1

1

7

Small-scale

0.621

High

557076

SRC
Proto-oncogene tyrosine-protein kinase Src

1

18

Small-scale

0.618

High

584468

VAV
Proto-oncogene vav

1

18

Small-scale

0.618

High

619204

CBL
E3 ubiquitin-protein ligase CBL

1

5

Small-scale

0.618

High

619209

SHC1
SHC-transforming protein 1

1

20

Small-scale

0.618

High

619212

KSYK
Tyrosine-protein kinase SYK

1

20

Small-scale

0.618

High

619217

RON
Macrophage-stimulating protein receptor

1

20

Small-scale

0.618

High

619232

FBW1A
F-box/WD repeat-containing protein 1A

1

6

Small-scale

0.618

High

599264

PLCG2
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2

1

7

Small-scale

0.590

High

619216

RACK1
Small ribosomal subunit protein RACK1

1

4

Small-scale

0.579

High

619223

ELOB
Elongin-B

1

1

Small-scale

0.579

High

471720

PTPRC
Receptor-type tyrosine-protein phosphatase C

1

20

High-throughput

0.575

High

619205

PTPRB
Receptor-type tyrosine-protein phosphatase beta

1

20

High-throughput

0.575

High

619206

PTPRG
Receptor-type tyrosine-protein phosphatase gamma

1

20

High-throughput

0.575

High

619219

PTPRJ
Receptor-type tyrosine-protein phosphatase eta

1

20

High-throughput

0.575

High

619224

PTPRO
Receptor-type tyrosine-protein phosphatase O

1

20

High-throughput

0.575

High

619210

VHL
von Hippel-Lindau disease tumor suppressor

1

0

Small-scale

0.537

High

619227

ATX2L
Ataxin-2-like protein

1

1

Small-scale

0.515

High

619225

RNF43
E3 ubiquitin-protein ligase RNF43

1

10

Small-scale

0.501

High

619231

ZNRF3
E3 ubiquitin-protein ligase ZNRF3

1

10

Small-scale

0.501

High

619215

GNAI1
Guanine nucleotide-binding protein G(i) subunit alpha-1

1

0

Small-scale

0.480

High

619234

IRS2
Insulin receptor substrate 2

1

5

Small-scale

0.479

High

619222

ELOC
Elongin-C

1

1

Small-scale

0.457

High

619226

RN128
E3 ubiquitin-protein ligase RNF128

1

7

Small-scale

0.457

High

619221

CUL2
Cullin-2

1

3

Small-scale

0.437

High

619229

EGLN3
Prolyl hydroxylase EGLN3

1

0

Small-scale

0.292

High

619233

NOSIP
Nitric oxide synthase-interacting protein

1

0

Small-scale

0.249

Low


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Last updated: 11Aug2025