HitPredict

Interactor 1: PRI2 (P20457)
DNA primase large subunit (DNA polymerase alpha:primase complex p58 subunit) (DNA polymerase-primase complex p58 subunit) (Pol alpha-primase complex p58 subunit) (DNA primase 58 kDa subunit)
Gene: PRI2

Interactor 2: DPOA2 (P38121)
DNA polymerase alpha subunit B (DNA polymerase I subunit B) (DNA polymerase alpha:primase complex p86 subunit) (Pol alpha-primase complex p86 subunit) (DNA polymerase-primase complex p74 subunit)
Gene: POL12

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.80	0.60	0.694

Property	Details
Experiments	11805826, 16429126, 37968396, 21715379
Identification Methods	tandem affinity purification, affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005635 - nuclear envelope GO:0005658 - alpha DNA polymerase:primase complex GO:0006270 - DNA replication initiation
Homologous interactions	2

Homologous interactions

Color coding for hit scores

	1 528 Sc			1 705
+	Sp
		251837 PRI2_SCHPO (55-507): 0: 519: 43.53		DPOA2_SCHPO (172-703): 0: 541: 32.52
+	Hs
		830170 PRI2_HUMAN (55-522): 0: 601: 35.31		DPOA2_HUMAN (247-673): 1.92e-147: 444: 26.81