HitPredict

Interactor 1: RCC1 (P18754)
Regulator of chromosome condensation (Cell cycle regulatory protein) (Chromosome condensation protein 1)
Gene: RCC1

Interactor 2: RANG (P43487)
Ran-specific GTPase-activating protein (Ran-binding protein 1) (RanBP1)
Gene: RANBP1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.81	0.60	0.699

Property	Details
Experiments	26186194, 28514442, 33961781, 35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0031267 - small GTPase binding
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 421 Hs			1 201
+	Hs
		483381 RCC1_HUMAN (1-421): 5.38e-164: 469: 100.00		RGPD1_HUMAN (1-201): 7.66e-48: 169: 34.80
+	Hs
		152761 RCC1_HUMAN (1-421): 5.38e-164: 469: 100.00		RGPD8_HUMAN (1-201): 9.54e-47: 166: 34.31
+	Hs
		578469 RCC1_HUMAN (1-421): 5.38e-164: 469: 100.00		RGPD5_HUMAN (1-201): 9.73e-47: 166: 34.31
+	Hs
		63873 RCC1_HUMAN (1-421): 5.38e-164: 469: 100.00		RGPD3_HUMAN (1-201): 2.17e-46: 165: 34.80
+	Hs
		578395 RCC1_HUMAN (1-421): 5.38e-164: 469: 100.00		RBP2_HUMAN (4-164): 1.49e-44: 160: 47.83
+	Hs
		578486 RCC1_HUMAN (1-421): 5.38e-164: 469: 100.00		RANB3_HUMAN (10-186): 4.16e-30: 117: 16.75
+	Sc
		601761 RCC1_YEAST (192-419): 1.22e-30: 124: 18.85		YRB1_YEAST (3-165): 2.48e-40: 137: 50.31
+	Sc
		601745 RCC1_YEAST (192-419): 1.22e-30: 124: 18.85		NUP2_YEAST (3-163): 8.78e-27: 108: 22.22
+	Sc
		601760 RCC1_YEAST (192-419): 1.22e-30: 124: 18.85		YRB2_YEAST (2-155): 4.17e-27: 106: 23.23