Protein: RGS4
Regulator of G-protein signaling 4 (RGP4) (RGS4)

Gene: RGS4
Organism: Homo sapiens
Interactions: 20
UniProt ID: P49798

Gene Ontology (top 5):
GO:0001965 - G-protein alpha-subunit binding
GO:0001975 - response to amphetamine
GO:0003924 - GTPase activity
GO:0005096 - GTPase activator activity
GO:0005516 - calmodulin binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

890697

GNAQ
Guanine nucleotide-binding protein G(q) subunit alpha

3

20

Small-scale

0.865

High

482589

GNAO
Guanine nucleotide-binding protein G(o) subunit alpha

2

20

Small-scale

0.778

High

890698

GNAI1
Guanine nucleotide-binding protein G(i) subunit alpha-1

2

20

Small-scale

0.778

High

890699

PAK2
Serine/threonine-protein kinase PAK 2

1

2

High-throughput

0.691

High

362977

EGFR
Epidermal growth factor receptor

4

4

Small-scale

0.687

High

773449

COPB2
Coatomer subunit beta'

1

1

Small-scale

0.662

High

418624

GNAI2
Guanine nucleotide-binding protein G(i) subunit alpha-2

1

20

Small-scale

0.647

High

890702

PPCEL
Prolyl endopeptidase-like

2

0

High-throughput

0.595

High

890706

KCMF1
E3 ubiquitin-protein ligase KCMF1

1

0

Small-scale

0.505

High

139116

KRIT1
Krev interaction trapped protein 1

1

3

Small-scale

0.501

High

890707

GABR1
Gamma-aminobutyric acid type B receptor subunit 1

1

1

Small-scale

0.501

High

890696

MTHFS
5-formyltetrahydrofolate cyclo-ligase

1

0

High-throughput

0.493

High

630144

ACM3
Muscarinic acetylcholine receptor M3

1

13

Small-scale

0.479

High

641529

ERBB3
Receptor tyrosine-protein kinase erbB-3

1

5

Small-scale

0.479

High

835433

GRM5
Metabotropic glutamate receptor 5

1

1

Small-scale

0.479

High

890700

SQSTM
Sequestosome-1

1

1

Small-scale

0.479

High

890701

EEA1
Early endosome antigen 1

1

3

High-throughput

0.479

High

890705

ESYT1
Extended synaptotagmin-1

1

1

High-throughput

0.479

High

890703

UBR1
E3 ubiquitin-protein ligase UBR1

1

1

Small-scale

0.408

High

890704

AEDO
2-aminoethanethiol dioxygenase

1

1

Small-scale

0.407

High


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Last updated: 11Aug2025