HitPredict

Interactor 1: RGS4 (P49799)
Regulator of G-protein signaling 4 (RGP4) (RGS4)
Gene: RGS4

Interactor 2: GNAO (P59215)
Guanine nucleotide-binding protein G(o) subunit alpha (EC 3.6.5.-)
Gene: Gnao1

Species: Rattus norvegicus

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	23022564
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	G-alpha~RGS
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 205 Rn			1 354
+	Hs
		482589 RGS4_HUMAN (1-205): 1.49e-81: 243: 97.07		GNAO_HUMAN (1-354): 1e-178: 500: 98.59
+	Hs
		418624 RGS4_HUMAN (1-205): 1.49e-81: 243: 97.07		GNAI2_HUMAN (1-354): 8.37e-174: 488: 68.45
+	Rn
		533208 RGS4_RAT (1-205): 7.33e-82: 243: 100.00		GNAI1_RAT (1-354): 1.94e-173: 487: 71.83
+	Hs
		890698 RGS4_HUMAN (1-205): 1.49e-81: 243: 97.07		GNAI1_HUMAN (1-354): 1.56e-173: 487: 71.83
+	Mm
		617637 RGS16_MOUSE (1-198): 7.7e-71: 215: 44.78		GNAO_MOUSE (1-354): 1.98e-176: 495: 99.44
+	Hs
		193880 RGS5_HUMAN (1-179): 8.39e-69: 209: 52.49		GNAO_HUMAN (1-354): 1e-178: 500: 98.59
+	Hs
		890697 RGS4_HUMAN (1-205): 1.49e-81: 243: 97.07		GNAQ_HUMAN (1-353): 5.62e-164: 464: 49.72
+	Hs
		192032 RGS16_HUMAN (1-177): 4.68e-67: 206: 48.89		GNAO_HUMAN (1-354): 1e-178: 500: 98.59
+	Hs
		418623 RGS3_HUMAN (16-184): 1.75e-64: 216: 52.66		GNAI2_HUMAN (1-354): 8.37e-174: 488: 68.45
+	Hs
		193876 RGS5_HUMAN (1-179): 8.39e-69: 209: 52.49		GNAI2_HUMAN (1-354): 8.37e-174: 488: 68.45
+	Hs
		193887 RGS5_HUMAN (1-179): 8.39e-69: 209: 52.49		GNAI1_HUMAN (1-354): 1.56e-173: 487: 71.83
+	Hs
		475923 RGS3_HUMAN (16-184): 1.75e-64: 216: 52.66		GNAI3_HUMAN (1-354): 4.07e-170: 479: 70.70
+	Hs
		192029 RGS16_HUMAN (1-177): 4.68e-67: 206: 48.89		GNAI2_HUMAN (1-354): 8.37e-174: 488: 68.45
+	Hs
		192036 RGS16_HUMAN (1-177): 4.68e-67: 206: 48.89		GNAI1_HUMAN (1-354): 1.56e-173: 487: 71.83
+	Hs
		193879 RGS5_HUMAN (1-179): 8.39e-69: 209: 52.49		GNAI3_HUMAN (1-354): 4.07e-170: 479: 70.70
+	Hs
		192031 RGS16_HUMAN (1-177): 4.68e-67: 206: 48.89		GNAI3_HUMAN (1-354): 4.07e-170: 479: 70.70
+	Hs
		193883 RGS5_HUMAN (1-179): 8.39e-69: 209: 52.49		GNAQ_HUMAN (1-353): 5.62e-164: 464: 49.72
+	Hs
		192035 RGS16_HUMAN (1-177): 4.68e-67: 206: 48.89		GNAQ_HUMAN (1-353): 5.62e-164: 464: 49.72
+	Hs
		715999 RGS3_HUMAN (16-184): 1.75e-64: 216: 52.66		GNA11_HUMAN (1-353): 6.54e-160: 453: 49.44
+	Hs
		192037 RGS16_HUMAN (1-177): 4.68e-67: 206: 48.89		GNA13_HUMAN (2-353): 3.31e-147: 422: 41.94