HitPredict

Interactor 1: ADA2B (P18089)
Alpha-2B adrenergic receptor (Alpha-2 adrenergic receptor subtype C2) (Alpha-2B adrenoreceptor) (Alpha-2B adrenoceptor) (Alpha-2BAR)
Gene: ADRA2B

Interactor 2: NEB2 (Q96SB3)
Neurabin-2 (Neurabin-II) (Protein phosphatase 1 regulatory subunit 9B) (Spinophilin)
Gene: PPP1R9B

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	11154706
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 450 Hs			1 817
+	Hs
		477192 ADA2A_HUMAN (5-448): 1.71e-87: 276: 48.77		NEB2_HUMAN (1-817): 1.91e-119: 382: 100.00
+	Hs
		572465 DRD2_HUMAN (15-443): 2.01e-84: 267: 28.84		NEB2_HUMAN (1-817): 1.91e-119: 382: 100.00
+	Rn
		204576 DRD2_RAT (15-443): 8.48e-85: 268: 30.00		NEB2_RAT (1-817): 2.34e-115: 371: 95.36
+	Hs
		630187 ACM3_HUMAN (10-445): 1.02e-76: 251: 18.60		NEB2_HUMAN (1-817): 1.91e-119: 382: 100.00
+	Hs
		616704 ADA2C_HUMAN (21-441): 1.48e-74: 242: 48.93		NEB2_HUMAN (1-817): 1.91e-119: 382: 100.00
+	Hs
		770826 ADA1B_HUMAN (359-443): 7.54e-29: 120: 42.35		NEB2_HUMAN (1-817): 1.91e-119: 382: 100.00
+	Mm
		958592 DRD2_MOUSE (15-443): 7.95e-85: 268: 30.00		DLG4_MOUSE (438-714): 8.52e-28: 122: 16.38
+	Ce
		107570 O17470_CAEEL (17-446): 4.23e-71: 239: 24.02		G1K0W3_CAEEL (463-754): 3.18e-18: 91.9: 15.26
+	Hs
		299745 DRD3_HUMAN (12-443): 2.23e-70: 229: 29.59		MPDZ_HUMAN (20-762): 3.63e-18: 92.3: 11.59
+	Hs
		669174 ADA1D_HUMAN (350-437): 1.33e-25: 111: 44.32		LNX1_HUMAN (273-773): 1.63e-31: 133: 13.79
+	Hs
		472222 ADRB1_HUMAN (353-443): 1.87e-28: 119: 41.94		DLG4_HUMAN (438-714): 5.31e-28: 122: 16.38
+	Rn
		528537 ADRB2_RAT (365-449): 2.29e-25: 109: 32.94		DLG4_RAT (438-714): 1.04e-27: 121: 16.38
+	Hs
		669165 ADA1D_HUMAN (350-437): 1.33e-25: 111: 44.32		DLG1_HUMAN (435-691): 6.13e-19: 94.1: 15.04
+	Hs
		472226 ADRB1_HUMAN (353-443): 1.87e-28: 119: 41.94		MAGI2_HUMAN (261-708): 1.7e-12: 73.5: 11.84
+	Hs
		472225 ADRB1_HUMAN (353-443): 1.87e-28: 119: 41.94		MAGI3_HUMAN (223-665): 1.28e-11: 70.8: 11.91
+	Hs
		458353 ADRB2_HUMAN (350-449): 1.44e-24: 107: 31.00		SYJ2B_HUMAN (496-589): 9.31e-18: 82.7: 27.66
+	Hs
		669170 ADA1D_HUMAN (350-437): 1.33e-25: 111: 44.32		SCRIB_HUMAN (412-596): 5.01e-14: 78.7: 21.15
+	Hs
		472228 ADRB1_HUMAN (353-443): 1.87e-28: 119: 41.94		MAGI1_HUMAN (462-691): 1.6e-10: 67.3: 10.35
+	Mm
		616491 ADRB2_MOUSE (350-449): 3.84e-26: 111: 31.00		MAGI3_MOUSE (223-665): 5.25e-11: 68.9: 12.14
+	Hs
		458428 ADRB2_HUMAN (350-449): 1.44e-24: 107: 31.00		MAGI3_HUMAN (223-665): 1.28e-11: 70.8: 11.91