HitPredict

Interactor 1: PSA7 (P21242)
Probable proteasome subunit alpha type-7 (Macropain subunit C1) (Multicatalytic endopeptidase complex subunit C1) (Proteasome component C1) (Proteinase YSCE subunit 1)
Gene: PRE10

Interactor 2: PSA6 (P40302)
Proteasome subunit alpha type-6 (Macropain subunit PRE5) (Multicatalytic endopeptidase complex subunit PRE5) (Proteasome component PRE5) (Proteinase YSCE subunit PRE5)
Gene: PRE5

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 1.00 0.970

The method score is based on:

Property Details
Experiments 11595789, 10688190, 19412159, 37968396, 15253422, 22940862, 16554755, 16429126, 31848235
Identification Methods two hybrid, affinity chromatography technology, cross-linking study, two hybrid array, tandem affinity purification
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Proteasome~Proteasome, Proteasome~Proteasome_A_N, Proteasome_A_N~Proteasome_A_N
Common GO terms GO:0000502 - proteasome complex
GO:0005634 - nucleus
GO:0010499 - proteasomal ubiquitin-independent protein catabolic process
GO:0019773 - proteasome core complex, alpha-subunit complex
GO:0034515 - proteasome storage granule
and 1 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 288
Sc

1 234
+ Sp
+ Hs
+ Hs
+ Dm
+ Dm
+ Dm
+ Hs
+ Hs
+ Hs
+ Dm
+ Dm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Dm
+ Sc

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Last updated: 11Aug2025