HitPredict

Interactor 1: MYL9 (P24844)
Myosin regulatory light polypeptide 9 (20 kDa myosin light chain) (LC20) (MLC-2C) (Myosin RLC) (Myosin regulatory light chain 2, smooth muscle isoform) (Myosin regulatory light chain 9) (Myosin regulatory light chain MRLC1)
Gene: MYL9

Interactor 2: CC141 (Q6ZP82)
Coiled-coil domain-containing protein 141 (Coiled-coil protein associated with myosin II and DISC1)
Gene: CCDC141

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	20956536
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	EF-hand_7~Spectrin
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 172 Hs			1 1530
+	Mm
		98240 MYL9_MOUSE (1-172): 1.02e-66: 202: 99.42		CC141_MOUSE (1-1530): 5.16e-104: 367: 72.65
+	Dm
		823750 SQH_DROME (1-172): 4.43e-61: 188: 80.46		SPTCB_DROME (103-1124): 2.77e-39: 162: 11.26
+	Dm
		561562 SQH_DROME (1-172): 4.43e-61: 188: 80.46		SPTCA_DROME (325-1149): 1.51e-36: 154: 11.59
+	Hs
		169066 ML12B_HUMAN (1-172): 9.17e-67: 203: 93.02		MYH11_HUMAN (467-1406): 2.87e-26: 120: 9.08
+	Hs
		618655 ML12A_HUMAN (15-172): 7.79e-65: 198: 94.30		MYH11_HUMAN (467-1406): 2.87e-26: 120: 9.08
+	Hs
		169045 ML12B_HUMAN (1-172): 9.17e-67: 203: 93.02		MYH7_HUMAN (504-1408): 4.06e-22: 106: 11.37
+	Hs
		169064 ML12B_HUMAN (1-172): 9.17e-67: 203: 93.02		MYH9_HUMAN (5-427): 3.15e-12: 74: 11.50
+	Hs
		533985 MLRV_HUMAN (9-166): 3.22e-54: 171: 57.23		MYH1_HUMAN (504-1379): 1.1e-21: 105: 10.85
+	Hs
		666740 MYL9_HUMAN (1-172): 1.53e-66: 202: 100.00		MYH9_HUMAN (5-427): 3.15e-12: 74: 11.50
+	Mm
		906631 MLRV_MOUSE (9-166): 2.18e-53: 168: 55.98		MYH6_MOUSE (504-1408): 1.41e-22: 107: 10.93
+	Hs
		169065 ML12B_HUMAN (1-172): 9.17e-67: 203: 93.02		MYH10_HUMAN (670-1379): 4.13e-11: 70.5: 9.55
+	Hs
		666741 MYL9_HUMAN (1-172): 1.53e-66: 202: 100.00		MYH10_HUMAN (670-1379): 4.13e-11: 70.5: 9.55
+	Hs
		618653 ML12A_HUMAN (15-172): 7.79e-65: 198: 94.30		MYH9_HUMAN (5-427): 3.15e-12: 74: 11.50
+	Mm
		1223376 Q6ZWQ9_MOUSE (1-172): 1.03e-66: 202: 93.61		MYH10_MOUSE (670-1379): 1.39e-10: 68.6: 9.27
+	Hs
		618654 ML12A_HUMAN (15-172): 7.79e-65: 198: 94.30		MYH10_HUMAN (670-1379): 4.13e-11: 70.5: 9.55
+	Dm
		823812 SQH_DROME (1-172): 4.43e-61: 188: 80.46		Q9VZQ3_DROME (53-1118): 2.57e-11: 71.4: 16.53
+	Ce
		109082 CALM_CAEEL (97-171): 2.63e-15: 70.7: 25.33		G4S034_CAEEL (56-1167): 3.8e-40: 166: 12.15
+	Hs
		516503 CALM3_HUMAN (97-171): 1.89e-15: 71: 25.33		SPTB2_HUMAN (103-1235): 5.18e-38: 158: 12.52
+	Dm
		614636 MLR_DROME (3-163): 7.61e-30: 110: 40.61		Q9W053_DROME (1042-1506): 2.18e-09: 64.7: 10.47
+	Hs
		516514 CALM3_HUMAN (97-171): 1.89e-15: 71: 25.33		SPTN1_HUMAN (420-1252): 5.32e-14: 79.9: 9.71