HitPredict

Interactor 1: MYL9 (P24844)
Myosin regulatory light polypeptide 9 (20 kDa myosin light chain) (LC20) (MLC-2C) (Myosin RLC) (Myosin regulatory light chain 2, smooth muscle isoform) (Myosin regulatory light chain 9) (Myosin regulatory light chain MRLC1)
Gene: MYL9

Interactor 2: MYH9 (P35579)
Myosin-9 (Cellular myosin heavy chain, type A) (Myosin heavy chain 9) (Myosin heavy chain, non-muscle IIa) (Non-muscle myosin heavy chain A) (NMMHC-A) (Non-muscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA)
Gene: MYH9

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.80 1.00 0.898

The method score is based on:

Property Details
Experiments 31839598, 16169070, 35271311, 28524877
Identification Methods cross-linking study, two hybrid, affinity chromatography technology, anti tag coimmunoprecipitation, two hybrid pooling approach
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains EF-hand_7~Myosin_head, EF-hand_7~Myosin_N, EF-hand_7~Myosin_tail_1
Common GO terms GO:0001725 - stress fiber
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0016460 - myosin II complex
GO:0070527 - platelet aggregation
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 172
Hs

1 1960
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+ Ce
+ Ce

Service provided by Combinatics, Japan

Last updated: 11Aug2025