HitPredict

Interactor 1: P121C (A8CG34)
Nuclear envelope pore membrane protein POM 121C (Nuclear pore membrane protein 121-2) (POM121-2) (Pore membrane protein of 121 kDa C)
Gene: POM121C

Interactor 2: IMA3 (O00629)
Importin subunit alpha-3 (Importin alpha Q1) (Qip1) (Karyopherin subunit alpha-4)
Gene: KPNA4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	35271311
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005643 - nuclear pore GO:0005654 - nucleoplasm GO:0006606 - protein import into nucleus GO:0008139 - nuclear localization sequence binding GO:0031965 - nuclear membrane
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 1229 Hs			1 521
+	Hs
		68005 P121C_HUMAN (1-1229): 2.98e-86: 308: 100.00		IMA4_HUMAN (1-521): 3.97e-160: 467: 85.80
+	Hs
		142603 P121A_HUMAN (1-1229): 1.41e-75: 276: 93.45		IMA3_HUMAN (1-521): 1.53e-163: 475: 100.00
+	Hs
		138745 P121A_HUMAN (1-1229): 1.41e-75: 276: 93.45		IMA4_HUMAN (1-521): 3.97e-160: 467: 85.80
+	Hs
		68012 P121C_HUMAN (1-1229): 2.98e-86: 308: 100.00		IMA1_HUMAN (1-521): 4.17e-143: 424: 49.44
+	Hs
		76076 B4DET5_HUMAN (371-1229): 8.92e-62: 230: 99.65		IMA3_HUMAN (1-521): 1.53e-163: 475: 100.00
+	Hs
		911050 P121A_HUMAN (1-1229): 1.41e-75: 276: 93.45		IMA1_HUMAN (1-521): 4.17e-143: 424: 49.44
+	Hs
		76075 B4DET5_HUMAN (371-1229): 8.92e-62: 230: 99.65		IMA4_HUMAN (1-521): 3.97e-160: 467: 85.80
+	Hs
		253676 P121A_HUMAN (1-1229): 1.41e-75: 276: 93.45		IMA7_HUMAN (1-521): 6.05e-140: 416: 46.46
+	Hs
		911339 P121A_HUMAN (1-1229): 1.41e-75: 276: 93.45		IMA5_HUMAN (3-521): 3.03e-133: 399: 45.46
+	Hs
		76104 B4DET5_HUMAN (371-1229): 8.92e-62: 230: 99.65		IMA1_HUMAN (1-521): 4.17e-143: 424: 49.44
+	Hs
		142643 NCOR2_HUMAN (4-1227): 2.04e-12: 74.5: 8.48		IMA3_HUMAN (1-521): 1.53e-163: 475: 100.00
+	Hs
		138638 NU214_HUMAN (148-1195): 5.27e-11: 69.6: 11.93		IMA4_HUMAN (1-521): 3.97e-160: 467: 85.80
+	Hs
		910949 POZP3_HUMAN (243-348): 3.3e-26: 109: 76.64		IMA1_HUMAN (1-521): 4.17e-143: 424: 49.44
+	Hs
		138713 ANR11_HUMAN (401-1184): 9.08e-09: 62.3: 12.08		IMA4_HUMAN (1-521): 3.97e-160: 467: 85.80
+	Xl
		909942 Q5EWX9_XENLA (279-1229): 9.5e-27: 120: 13.43		IMA5_XENLA (3-521): 1.34e-132: 396: 47.71
+	Hs
		910821 NUP98_HUMAN (784-1215): 1.88e-09: 64.3: 20.76		IMA1_HUMAN (1-521): 4.17e-143: 424: 49.44
+	Hs
		253645 ANR11_HUMAN (401-1184): 9.08e-09: 62.3: 12.08		IMA7_HUMAN (1-521): 6.05e-140: 416: 46.46
+	Hs
		911192 NUP98_HUMAN (784-1215): 1.88e-09: 64.3: 20.76		IMA5_HUMAN (3-521): 3.03e-133: 399: 45.46