HitPredict

Interactor 1: IMA1 (P52292)
Importin subunit alpha-1 (Karyopherin subunit alpha-2) (RAG cohort protein 1) (SRP1-alpha)
Gene: KPNA2

Interactor 2: NUP98 (P52948)
Nuclear pore complex protein Nup98-Nup96 (EC 3.4.21.-) [Cleaved into: Nuclear pore complex protein Nup98 (98 kDa nucleoporin) (Nucleoporin Nup98) (Nup98); Nuclear pore complex protein Nup96 (96 kDa nucleoporin) (Nucleoporin Nup96) (Nup96)]
Gene: NUP98

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	38514841, 38507240
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0006606 - protein import into nucleus GO:0008139 - nuclear localization sequence binding and 1 others more... GO:0031965 - nuclear membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 529 Hs			1 1817
+	Hs
		890282 IMA1_HUMAN (1-529): 6.81e-163: 474: 100.00		NU153_HUMAN (90-599): 2.83e-12: 74.4: 15.32
+	Hs
		911138 IMA1_HUMAN (1-529): 6.81e-163: 474: 100.00		CHD7_HUMAN (2-355): 6.5e-12: 73.2: 9.09
+	Hs
		911050 IMA1_HUMAN (1-529): 6.81e-163: 474: 100.00		P121A_HUMAN (95-741): 7.27e-09: 63.2: 9.63
+	Hs
		138638 IMA4_HUMAN (4-529): 2.57e-146: 432: 49.25		NU214_HUMAN (70-677): 6.48e-19: 96.4: 12.06
+	At
		102358 IMPA2_ARATH (1-529): 6.22e-154: 452: 44.65		NUP1_ARATH (1-432): 1.17e-12: 75.6: 15.47
+	At
		146478 IMPA3_ARATH (1-529): 2.91e-154: 452: 44.32		NUP1_ARATH (1-432): 1.17e-12: 75.6: 15.47
+	At
		1379673 IMPA1_ARATH (1-529): 2.05e-153: 450: 45.00		NUP1_ARATH (1-432): 1.17e-12: 75.6: 15.47
+	Hs
		142505 IMA3_HUMAN (4-529): 4.71e-150: 441: 50.10		NU153_HUMAN (90-599): 2.83e-12: 74.4: 15.32
+	Hs
		138653 IMA4_HUMAN (4-529): 2.57e-146: 432: 49.25		NU153_HUMAN (90-599): 2.83e-12: 74.4: 15.32
+	Sp
		313992 IMA2_SCHPO (11-529): 1.58e-137: 410: 46.70		NU124_SCHPO (23-551): 9.9e-19: 95.5: 16.28
+	Hs
		142603 IMA3_HUMAN (4-529): 4.71e-150: 441: 50.10		P121A_HUMAN (95-741): 7.27e-09: 63.2: 9.63
+	Sc
		1037951 IMA1_YEAST (2-529): 5.44e-138: 411: 43.83		NU100_YEAST (123-761): 6.69e-17: 89.4: 10.75
+	Hs
		138745 IMA4_HUMAN (4-529): 2.57e-146: 432: 49.25		P121A_HUMAN (95-741): 7.27e-09: 63.2: 9.63
+	Hs
		253601 IMA7_HUMAN (1-528): 2.65e-140: 417: 45.37		NU153_HUMAN (90-599): 2.83e-12: 74.4: 15.32
+	Sc
		1037972 IMA1_YEAST (2-529): 5.44e-138: 411: 43.83		NU116_YEAST (182-770): 5.42e-14: 79.8: 10.87
+	Sc
		1035264 IMA1_YEAST (2-529): 5.44e-138: 411: 43.83		NUP49_YEAST (1-184): 2.3e-13: 76.6: 27.60
+	Hs
		179034 IMA6_HUMAN (1-528): 6.67e-136: 406: 45.02		NU153_HUMAN (90-599): 2.83e-12: 74.4: 15.32
+	Hs
		253676 IMA7_HUMAN (1-528): 2.65e-140: 417: 45.37		P121A_HUMAN (95-741): 7.27e-09: 63.2: 9.63
+	Sc
		877973 IMA1_YEAST (2-529): 5.44e-138: 411: 43.83		NUP57_YEAST (1-164): 1.91e-10: 67.7: 27.06
+	Dm
		1465451 Q9V455_DROME (7-529): 2.19e-133: 398: 47.52		Q9VGL0_DROME (5-482): 7.78e-14: 79.4: 14.88