HitPredict

Interactor 1: P121C (A8CG34)
Nuclear envelope pore membrane protein POM 121C (Nuclear pore membrane protein 121-2) (POM121-2) (Pore membrane protein of 121 kDa C)
Gene: POM121C

Interactor 2: DYR1B (Q9Y463)
Dual specificity tyrosine-phosphorylation-regulated kinase 1B (EC 2.7.12.1) (Minibrain-related kinase) (Mirk protein kinase)
Gene: DYRK1B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	32707033
Identification Methods	pull down
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 1229 Hs			1 629
+	Hs
		76163 B4DET5_HUMAN (371-1229): 8.92e-62: 230: 99.65		DYR1B_HUMAN (1-629): 3.03e-172: 506: 100.00
+	Hs
		1115903 P121A_HUMAN (1-1229): 1.41e-75: 276: 93.45		DYR1A_HUMAN (19-592): 5.24e-136: 417: 62.59
+	Hs
		1116183 PCLO_HUMAN (277-1224): 3.75e-31: 136: 11.15		DYR1A_HUMAN (19-592): 5.24e-136: 417: 62.59
+	Hs
		1116007 TARA_HUMAN (11-1210): 8.29e-20: 98.8: 9.17		DYR1A_HUMAN (19-592): 5.24e-136: 417: 62.59
+	Hs
		353775 APCL_HUMAN (1-915): 7.13e-18: 92.2: 9.50		DYR1A_HUMAN (19-592): 5.24e-136: 417: 62.59
+	Hs
		1116179 NCOR2_HUMAN (4-1227): 2.04e-12: 74.5: 8.48		DYR1A_HUMAN (19-592): 5.24e-136: 417: 62.59
+	Hs
		1115795 ANKH1_HUMAN (453-1171): 2.83e-11: 70.5: 15.06		DYR1A_HUMAN (19-592): 5.24e-136: 417: 62.59
+	Hs
		775536 NU214_HUMAN (148-1195): 5.27e-11: 69.6: 11.93		DYR1A_HUMAN (19-592): 5.24e-136: 417: 62.59
+	Hs
		915958 NUP98_HUMAN (784-1215): 1.88e-09: 64.3: 20.76		DYR1A_HUMAN (19-592): 5.24e-136: 417: 62.59
+	Hs
		161464 KMT2D_HUMAN (549-1219): 3.16e-09: 64: 11.50		DYR1A_HUMAN (19-592): 5.24e-136: 417: 62.59
+	Hs
		274213 ANR17_HUMAN (282-1164): 8.84e-23: 108: 14.54		DYRK2_HUMAN (9-483): 8.72e-118: 365: 34.32
+	Hs
		1366128 TARA_HUMAN (11-1210): 8.29e-20: 98.8: 9.17		DYRK2_HUMAN (9-483): 8.72e-118: 365: 34.32
+	At
		100035 NP214_ARATH (529-1164): 2.57e-20: 100: 17.61		KSG7_ARATH (80-475): 8.55e-116: 352: 26.14
+	Hs
		728504 NCOR2_HUMAN (4-1227): 2.04e-12: 74.5: 8.48		AKT1_HUMAN (7-446): 7.14e-119: 364: 17.98
+	Hs
		668095 NCOR2_HUMAN (4-1227): 2.04e-12: 74.5: 8.48		CDK2_HUMAN (108-376): 2.34e-118: 355: 27.82
+	Hs
		1366145 SRRM2_HUMAN (40-605): 5.25e-09: 63.3: 12.37		DYRK2_HUMAN (9-483): 8.72e-118: 365: 34.32
+	Hs
		161418 KMT2D_HUMAN (549-1219): 3.16e-09: 64: 11.50		AKT1_HUMAN (7-446): 7.14e-119: 364: 17.98
+	Hs
		668075 SRRM2_HUMAN (40-605): 5.25e-09: 63.3: 12.37		CDK2_HUMAN (108-376): 2.34e-118: 355: 27.82
+	Hs
		889522 SRRM2_HUMAN (40-605): 5.25e-09: 63.3: 12.37		CLK1_HUMAN (64-431): 1.5e-49: 181: 31.14