HitPredict

Interactor 1: 1433B (P31946)
14-3-3 protein beta/alpha (Protein 1054) (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein beta/alpha, N-terminally processed]
Gene: YWHAB

Interactor 2: UBP54 (Q70EL1)
Inactive ubiquitin carboxyl-terminal hydrolase 54 (Inactive ubiquitin-specific peptidase 54)
Gene: USP54

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.50	0.609

Property	Details
Experiments	35271311, 36931259, 24255178
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 246 Hs			1 1684
+	Hs
		909723 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		UBP54_HUMAN (1-1684): 0: 2297: 100.00
+	Hs
		927205 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		UBP54_HUMAN (1-1684): 0: 2297: 100.00
+	Hs
		647033 1433T_HUMAN (3-244): 3.24e-127: 361: 81.82		UBP54_HUMAN (1-1684): 0: 2297: 100.00
+	Hs
		904761 1433G_HUMAN (3-246): 1.91e-109: 317: 75.40		UBP54_HUMAN (1-1684): 0: 2297: 100.00
+	Hs
		927542 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		UBP42_HUMAN (24-881): 5.02e-104: 366: 13.96
+	Hs
		904760 1433G_HUMAN (3-246): 1.91e-109: 317: 75.40		UBP53_HUMAN (1-940): 4.81e-128: 430: 34.38
+	Hs
		647288 1433T_HUMAN (3-244): 3.24e-127: 361: 81.82		UBP42_HUMAN (24-881): 5.02e-104: 366: 13.96
+	Mm
		910244 1433E_MOUSE (3-243): 4.39e-144: 405: 65.43		UBP48_MOUSE (8-529): 1.18e-82: 297: 12.46
+	Mm
		926789 1433Z_MOUSE (3-244): 3.14e-142: 399: 88.02		UBP48_MOUSE (8-529): 1.18e-82: 297: 12.46
+	Zm
		22585 B6U284_MAIZE (3-243): 6.61e-144: 404: 63.27		A0A1D6I2F1_MAIZE (4-669): 1.97e-80: 291: 12.20
+	Hs
		905373 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		UBP46_HUMAN (7-353): 8.59e-87: 290: 16.53
+	Hs
		683244 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		UBP46_HUMAN (7-353): 8.59e-87: 290: 16.53
+	Mm
		1113579 1433B_MOUSE (1-246): 5.56e-141: 396: 98.78		UBP48_MOUSE (8-529): 1.18e-82: 297: 12.46
+	Hs
		259266 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		UBP12_HUMAN (8-353): 5.69e-86: 287: 16.85
+	Hs
		905375 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		UBP46_HUMAN (7-353): 8.59e-87: 290: 16.53
+	Mm
		933121 1433T_MOUSE (3-244): 9.37e-127: 360: 81.82		UBP48_MOUSE (8-529): 1.18e-82: 297: 12.46
+	Hs
		647384 1433T_HUMAN (3-244): 3.24e-127: 361: 81.82		UBP22_HUMAN (2-352): 7.48e-85: 290: 15.42
+	Mm
		905335 1433G_MOUSE (3-246): 1.91e-109: 317: 75.40		UBP48_MOUSE (8-529): 1.18e-82: 297: 12.46
+	Hs
		904415 1433G_HUMAN (3-246): 1.91e-109: 317: 75.40		UBP46_HUMAN (7-353): 8.59e-87: 290: 16.53
+	Hs
		259272 1433G_HUMAN (3-246): 1.91e-109: 317: 75.40		UBP12_HUMAN (8-353): 5.69e-86: 287: 16.85