Interactor 1: RPN2 (P32565)
26S proteasome regulatory subunit RPN2
Gene: RPN2

Interactor 2: RPN1 (P38764)
26S proteasome regulatory subunit RPN1 (HMG-CoA reductase degradation protein 2) (Proteasome non-ATPase subunit 1)
Gene: RPN1

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 1.00 0.979

The method score is based on:

Property Details
Experiments 18511945, 22940862, 10873636, 9741626, 9584156, 16554755, 16429126, 19446323, 37968396, 21658604, 22237024, 14759368
Identification Methods cross-linking study, affinity chromatography technology, biochemical, pull down, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains PC_rep~PC_rep, PC_rep~RPN1_RPN2_N, RPN1_RPN2_N~RPN2_C
Common GO terms GO:0000502 - proteasome complex
GO:0005634 - nucleus
GO:0006511 - ubiquitin-dependent protein catabolic process
GO:0008540 - proteasome regulatory particle, base subcomplex
GO:0030234 - enzyme regulator activity
and 3 others

more...

Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 945
Sc

1 993
+ Hs
+ At
+ At
+ Hs
+ Sp
+ Hs
+ Hs
+ Dm
+ Sc
+ Sc

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Last updated: 15 Jul 2024