HitPredict

Interactor 1: BMI1 (P35226)
Polycomb complex protein BMI-1 (Polycomb group RING finger protein 4) (RING finger protein 51)
Gene: BMI1

Interactor 2: SCMH1 (Q96GD3)
Polycomb protein SCMH1 (Sex comb on midleg homolog 1)
Gene: SCMH1

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.80	0.60	0.694

Property	Details
Experiments	24981860, 24457600, 33961781, 22325352
Identification Methods	affinity chromatography technology, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 326 Hs			1 660
+	Hs
		718418 PCGF2_HUMAN (1-320): 1.04e-117: 344: 61.36		SCMH1_HUMAN (1-660): 0: 785: 100.00
+	Hs
		1220909 R4GMX3_HUMAN (1-326): 5.65e-157: 449: 100.00		PHC2_HUMAN (209-658): 2.19e-86: 290: 18.09
+	Hs
		717999 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		PHC2_HUMAN (209-658): 2.19e-86: 290: 18.09
+	Mm
		639480 BMI1_MOUSE (1-326): 2.15e-150: 426: 96.93		PHC2_MOUSE (209-658): 1.15e-85: 288: 17.61
+	Hs
		718028 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		PHC3_HUMAN (231-658): 6.64e-66: 235: 20.73
+	Mm
		639476 BMI1_MOUSE (1-326): 2.15e-150: 426: 96.93		PHC3_MOUSE (231-658): 9.6e-67: 238: 20.09
+	Hs
		717684 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		PHC1_HUMAN (296-657): 2.38e-59: 217: 19.06
+	Mm
		639473 BMI1_MOUSE (1-326): 2.15e-150: 426: 96.93		PHC1_MOUSE (234-657): 5.58e-59: 216: 17.30
+	Hs
		718408 PCGF2_HUMAN (1-320): 1.04e-117: 344: 61.36		PHC2_HUMAN (209-658): 2.19e-86: 290: 18.09
+	Dr
		1225025 BMI1A_DANRE (1-326): 9.35e-128: 369: 81.29		PHC2_DANRE (231-658): 3.02e-73: 254: 17.90
+	Hs
		718083 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		LMBL2_HUMAN (1-315): 5.74e-50: 187: 19.32
+	Dr
		1186373 BMI1B_DANRE (1-322): 4e-124: 360: 77.23		PHC2_DANRE (231-658): 3.02e-73: 254: 17.90
+	Hs
		718412 PCGF2_HUMAN (1-320): 1.04e-117: 344: 61.36		PHC3_HUMAN (231-658): 6.64e-66: 235: 20.73
+	Mm
		620790 PCGF2_MOUSE (1-320): 5.49e-113: 332: 61.06		PHC3_MOUSE (231-658): 9.6e-67: 238: 20.09
+	Hs
		718390 PCGF2_HUMAN (1-320): 1.04e-117: 344: 61.36		PHC1_HUMAN (296-657): 2.38e-59: 217: 19.06
+	Hs
		718311 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		SCML1_HUMAN (477-659): 5.31e-27: 114: 33.00
+	Mm
		620786 PCGF2_MOUSE (1-320): 5.49e-113: 332: 61.06		PHC1_MOUSE (234-657): 5.58e-59: 216: 17.30
+	Hs
		718330 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		SCML2_HUMAN (1-126): 2.16e-23: 107: 26.00
+	Hs
		718416 PCGF2_HUMAN (1-320): 1.04e-117: 344: 61.36		LMBL2_HUMAN (1-315): 5.74e-50: 187: 19.32
+	Hs
		718440 PCGF2_HUMAN (1-320): 1.04e-117: 344: 61.36		SCML1_HUMAN (477-659): 5.31e-27: 114: 33.00