HitPredict

Interactor 1: DLG1 (Q12959)
Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (SAP97) (hDlg)
Gene: DLG1

Interactor 2: NMDE3 (Q14957)
Glutamate receptor ionotropic, NMDA 2C (GluN2C) (Glutamate [NMDA] receptor subunit epsilon-3) (N-methyl D-aspartate receptor subtype 2C) (NMDAR2C) (NR2C)
Gene: GRIN2C

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	30126976
Identification Methods	p8 filamentous phage display
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005789 - endoplasmic reticulum membrane GO:0005886 - plasma membrane GO:0098839 - postsynaptic density membrane GO:0098978 - glutamatergic synapse
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 904 Hs			1 1233
+	Rn
		962671 DLG3_RAT (99-904): 0: 590: 64.57		NMDE3_RAT (1-1233): 0: 1263: 87.62
+	Hs
		1021485 DLG1_HUMAN (1-904): 0: 725: 100.00		NMDE2_HUMAN (6-950): 0: 809: 52.78
+	Mm
		963751 DLG1_MOUSE (1-904): 0: 720: 95.47		NMDE2_MOUSE (6-950): 0: 804: 52.57
+	Rn
		962663 DLG1_RAT (1-904): 0: 701: 92.54		NMDE2_RAT (6-950): 0: 808: 52.67
+	Hs
		1018888 DLG1_HUMAN (1-904): 0: 725: 100.00		NMDE1_HUMAN (1-921): 0: 738: 55.01
+	Rn
		962655 DLG1_RAT (1-904): 0: 701: 92.54		NMDE1_RAT (1-921): 0: 751: 54.58
+	Hs
		1021483 DLG1_HUMAN (1-904): 0: 725: 100.00		GRIK2_HUMAN (12-904): 0: 691: 18.97
+	Rn
		962664 DLG3_RAT (99-904): 0: 590: 64.57		NMDE2_RAT (6-950): 0: 808: 52.67
+	Mm
		936175 DLG3_MOUSE (99-904): 0: 589: 64.69		NMDE2_MOUSE (6-950): 0: 804: 52.57
+	Hs
		178307 DLG1_HUMAN (1-904): 0: 725: 100.00		NMDE4_HUMAN (30-868): 0: 649: 62.95
+	Hs
		786696 DLG1_HUMAN (1-904): 0: 725: 100.00		GRIA1_HUMAN (9-911): 0: 646: 20.67
+	Hs
		984257 DLG1_HUMAN (1-904): 0: 725: 100.00		NMDZ1_HUMAN (9-936): 0: 642: 22.91
+	Mm
		723600 DLG1_MOUSE (1-904): 0: 720: 95.47		NMDZ1_MOUSE (9-936): 0: 643: 22.91
+	Mm
		1142965 DLG1_MOUSE (1-904): 0: 720: 95.47		GRID2_MOUSE (10-984): 0: 636: 19.36
+	Rn
		585151 DLG1_RAT (1-904): 0: 701: 92.54		GRIA1_RAT (7-867): 0: 649: 21.51
+	Rn
		962656 DLG3_RAT (99-904): 0: 590: 64.57		NMDE1_RAT (1-921): 0: 751: 54.58
+	Rn
		1144011 DLG1_RAT (1-904): 0: 701: 92.54		GRID2_RAT (11-984): 0: 638: 19.08
+	Mm
		620881 DLG3_MOUSE (99-904): 0: 589: 64.69		GRIA1_MOUSE (7-867): 0: 646: 21.51
+	Rn
		723628 DLG3_RAT (99-904): 0: 590: 64.57		NMDZ1_RAT (9-936): 0: 643: 23.01
+	Mm
		723568 DLG3_MOUSE (99-904): 0: 589: 64.69		NMDZ1_MOUSE (9-936): 0: 643: 22.91