HitPredict

Interactor 1: B4DUB1 (B4DUB1)
cDNA FLJ50029, highly similar to Cell division cycle 2-like protein kinase 6
Gene: B4DUB1

Interactor 2: MED1 (Q15648)
Mediator of RNA polymerase II transcription subunit 1 (Activator-recruited cofactor 205 kDa component) (ARC205) (Mediator complex subunit 1) (Peroxisome proliferator-activated receptor-binding protein) (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TR-interacting protein 2) (TRIP-2) (Vitamin D receptor-interacting protein complex component DRIP205) (p53 regulatory protein RB18A)
Gene: MED1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	28514442
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 378 Hs			1 1581
+	Hs
		1076198 CDK19_HUMAN (3-378): 9.28e-111: 334: 94.15		MED1_HUMAN (1-1581): 0: 1281: 100.00
+	Hs
		826280 CDK8_HUMAN (3-378): 4.08e-109: 329: 65.43		MED1_HUMAN (1-1581): 0: 1281: 100.00
+	Hs
		647588 MK03_HUMAN (2-258): 3.74e-89: 275: 30.89		MED1_HUMAN (1-1581): 0: 1281: 100.00
+	Dm
		1371736 CDK8_DROME (3-248): 4.94e-97: 297: 76.42		MED1_DROME (8-1446): 3.39e-45: 181: 18.40
+	Hs
		826275 CDK8_HUMAN (3-378): 4.08e-109: 329: 65.43		MDC1_HUMAN (751-1577): 1.19e-16: 88.6: 8.40
+	Hs
		826294 CDK8_HUMAN (3-378): 4.08e-109: 329: 65.43		NIPBL_HUMAN (984-1563): 7.42e-16: 86.1: 16.01
+	Rn
		926487 MK01_RAT (2-256): 2.36e-89: 275: 28.79		SYNJ1_RAT (536-992): 7.47e-09: 62.8: 13.49
+	Hs
		841244 CDK7_HUMAN (28-230): 1.6e-29: 118: 38.42		ANR11_HUMAN (534-1294): 1.03e-12: 75.9: 7.58