HitPredict

Interactor 1: SH3GH (B1V8A0)
Endophilin-A homolog (Endophilin-1 homolog) (Uncoordinated protein 57)
Gene: unc-57

Interactor 2: DYN1 (P39055)
Dynamin (EC 3.6.5.5)
Gene: dyn-1

Species: Caenorhabditis elegans

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	0.60	0.457

Property	Details
Experiments	23549480
Identification Methods	two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0070266 - necroptotic process
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 381 Ce			1 830
+	Hs
		1050710 SH3G1_HUMAN (1-380): 1.64e-79: 250: 44.76		DYN1_HUMAN (5-820): 0: 996: 62.07
+	Mm
		810525 SH3G1_MOUSE (1-380): 8.17e-79: 248: 44.76		DYN1_MOUSE (5-826): 0: 995: 62.05
+	Mm
		810527 SH3G3_MOUSE (1-380): 7.79e-78: 245: 43.98		DYN1_MOUSE (5-826): 0: 995: 62.05
+	Hs
		1050711 SH3G2_HUMAN (1-380): 5.42e-77: 243: 42.93		DYN1_HUMAN (5-820): 0: 996: 62.07
+	Hs
		1408384 SH3G1_HUMAN (1-380): 1.64e-79: 250: 44.76		DYN3_HUMAN (5-830): 0: 987: 62.43
+	Hs
		1408425 SH3G3_HUMAN (1-380): 1.25e-79: 249: 43.98		DYN3_HUMAN (5-830): 0: 987: 62.43
+	Rn
		205730 SH3G1_RAT (1-380): 9.13e-78: 245: 45.03		DYN1_RAT (5-820): 0: 991: 62.31
+	Mm
		810526 SH3G2_MOUSE (1-380): 2.91e-76: 241: 42.67		DYN1_MOUSE (5-826): 0: 995: 62.05
+	Rn
		204407 SH3G2_RAT (1-380): 2.5e-76: 241: 42.41		DYN1_RAT (5-820): 0: 991: 62.31
+	Rn
		204411 SH3G3_RAT (1-380): 2.09e-76: 241: 43.46		DYN1_RAT (5-820): 0: 991: 62.31
+	Hs
		896871 SH3G1_HUMAN (1-380): 1.64e-79: 250: 44.76		DYN2_HUMAN (5-830): 0: 982: 63.05
+	Hs
		896873 SH3G3_HUMAN (1-380): 1.25e-79: 249: 43.98		DYN2_HUMAN (5-830): 0: 982: 63.05
+	Hs
		1408402 SH3G2_HUMAN (1-380): 5.42e-77: 243: 42.93		DYN3_HUMAN (5-830): 0: 987: 62.43
+	Hs
		896872 SH3G2_HUMAN (1-380): 5.42e-77: 243: 42.93		DYN2_HUMAN (5-830): 0: 982: 63.05
+	Mm
		810540 SHLB1_MOUSE (10-378): 2.11e-63: 208: 19.69		DYN1_MOUSE (5-826): 0: 995: 62.05
+	Dm
		693527 SH3G3_DROME (1-380): 8.73e-73: 233: 44.88		DYN_DROME (8-830): 0: 949: 65.58
+	Hs
		1050698 NOSTN_HUMAN (5-379): 2.21e-43: 159: 15.34		DYN1_HUMAN (5-820): 0: 996: 62.07
+	Mm
		810561 PACN2_MOUSE (3-378): 4.86e-43: 158: 12.64		DYN2_MOUSE (5-830): 0: 986: 63.59
+	Hs
		135692 SH3G1_HUMAN (1-380): 1.64e-79: 250: 44.76		DNM1L_HUMAN (8-744): 0: 795: 37.95
+	Hs
		135709 SHLB2_HUMAN (10-377): 1.75e-57: 194: 21.03		DNM1L_HUMAN (8-744): 0: 795: 37.95