HitPredict

Interactor 1: LSM1 (P47017)
Sm-like protein LSm1 (SPB8 protein)
Gene: LSM1

Interactor 2: LSM7 (P53905)
U6 snRNA-associated Sm-like protein LSm7
Gene: LSM7

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.94	1.00	0.974

Property	Details
Experiments	10747033, 10428970, 11805826, 16554755, 17513695, 18719247, 19111170, 37968396, 22450758, 16429126
Identification Methods	affinity chromatography technology, two hybrid, tandem affinity purification, biochemical
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	LSM~LSM
Common GO terms	GO:0000290 - deadenylation-dependent decapping of nuclear-transcribed mRNA GO:0000932 - P-body GO:0005634 - nucleus GO:0005737 - cytoplasm GO:1990726 - Lsm1-7-Pat1 complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 172 Sc			1 115
+	Sc
		810514 LSM1_YEAST (1-172): 4.98e-64: 196: 100.00		LSM1_YEAST (3-110): 2.93e-28: 102: 28.57
+	Sc
		810530 LSM1_YEAST (1-172): 4.98e-64: 196: 100.00		LSM3_YEAST (25-110): 2.58e-21: 82.7: 31.03
+	At
		1228013 LSM1B_ARATH (28-162): 5.17e-37: 125: 32.59		LSM7_ARATH (23-111): 3.06e-29: 103: 46.07
+	Dm
		1368680 Q9W2K2_DROME (36-165): 9.12e-32: 112: 40.00		Q9VJI7_DROME (8-111): 4.3e-31: 108: 41.35
+	Hs
		167663 LSM1_HUMAN (38-164): 1.07e-33: 117: 36.22		RSMB_HUMAN (23-103): 1.03e-27: 103: 28.40
+	Hs
		167725 LSM1_HUMAN (38-164): 1.07e-33: 117: 36.22		LSM7_HUMAN (18-111): 2.12e-29: 103: 46.81
+	Dm
		1368679 Q9W087_DROME (44-136): 1.83e-30: 108: 26.60		Q9VJI7_DROME (8-111): 4.3e-31: 108: 41.35
+	Sp
		251599 LSM7_SCHPO (11-120): 3.83e-29: 105: 23.21		LSM7_SCHPO (12-111): 7.11e-31: 107: 44.00
+	Hs
		321392 LSM8_HUMAN (43-135): 8.57e-29: 104: 32.98		RSMN_HUMAN (23-103): 1.07e-28: 105: 28.40
+	Hs
		321370 LSM8_HUMAN (43-135): 8.57e-29: 104: 32.98		RSMB_HUMAN (23-103): 1.03e-27: 103: 28.40
+	Hs
		321438 LSM8_HUMAN (43-135): 8.57e-29: 104: 32.98		LSM7_HUMAN (18-111): 2.12e-29: 103: 46.81
+	Hs
		167680 LSM1_HUMAN (38-164): 1.07e-33: 117: 36.22		LSM3_HUMAN (23-104): 3.17e-23: 87.7: 28.24
+	Hs
		167679 LSM1_HUMAN (38-164): 1.07e-33: 117: 36.22		RUXG_HUMAN (24-107): 3.5e-23: 86.9: 33.33
+	Mm
		912216 LSM1_MOUSE (38-164): 3.13e-33: 116: 37.01		LSM3_MOUSE (23-104): 3.17e-23: 87.7: 28.24
+	Dm
		1213200 Q9W087_DROME (44-136): 1.83e-30: 108: 26.60		Q8IMX8_DROME (23-104): 2.86e-23: 88.1: 27.06
+	Hs
		321387 LSM8_HUMAN (43-135): 8.57e-29: 104: 32.98		LSM3_HUMAN (23-104): 3.17e-23: 87.7: 28.24
+	Mm
		912214 LSM8_MOUSE (43-135): 8.57e-29: 104: 32.98		LSM3_MOUSE (23-104): 3.17e-23: 87.7: 28.24
+	Sc
		865977 LSM7_YEAST (8-119): 4.92e-26: 97.5: 27.97		LSM3_YEAST (25-110): 2.58e-21: 82.7: 31.03
+	Sc
		766934 LSM7_YEAST (8-119): 4.92e-26: 97.5: 27.97		RSMB_YEAST (23-107): 9.03e-19: 78.9: 28.13
+	Hs
		68412 RSMN_HUMAN (42-118): 8.26e-24: 95.1: 28.24		RUXGL_HUMAN (24-107): 5.73e-21: 81.1: 32.14