HitPredict

Interactor 1: DYN1 (P39053)
Dynamin-1 (EC 3.6.5.5) (Dynamin) (Dynamin I)
Gene: Dnm1

Interactor 2: SHLB1 (Q9JK48)
Endophilin-B1 (SH3 domain-containing GRB2-like protein B1)
Gene: Sh3glb1

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	12456676
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0042803 - protein homodimerization activity
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 867 Mm			1 365
+	Mm
		810527 DYN1_MOUSE (1-867): 0: 1086: 100.00		SH3G3_MOUSE (13-364): 2.97e-77: 243: 23.81
+	Mm
		810526 DYN1_MOUSE (1-867): 0: 1086: 100.00		SH3G2_MOUSE (13-364): 5.44e-74: 234: 26.33
+	Mm
		810525 DYN1_MOUSE (1-867): 0: 1086: 100.00		SH3G1_MOUSE (13-364): 1.04e-68: 221: 24.93
+	Hs
		1050711 DYN1_HUMAN (1-845): 0: 1050: 99.65		SH3G2_HUMAN (13-364): 2.18e-74: 236: 25.77
+	Rn
		204411 DYN1_RAT (1-845): 0: 1042: 98.34		SH3G3_RAT (13-364): 2.5e-75: 238: 24.37
+	Rn
		204407 DYN1_RAT (1-845): 0: 1042: 98.34		SH3G2_RAT (13-364): 4.02e-74: 235: 26.05
+	Hs
		1050710 DYN1_HUMAN (1-845): 0: 1050: 99.65		SH3G1_HUMAN (13-364): 4.59e-69: 222: 24.60
+	Rn
		205730 DYN1_RAT (1-845): 0: 1042: 98.34		SH3G1_RAT (13-364): 2.88e-68: 220: 24.60
+	Mm
		810523 DYN1_MOUSE (1-867): 0: 1086: 100.00		PACN1_MOUSE (10-364): 1.17e-43: 158: 13.02
+	Hs
		1050724 DYN1_HUMAN (1-845): 0: 1050: 99.65		PACN2_HUMAN (2-364): 4.07e-47: 168: 14.47
+	Rn
		638965 DYN1_RAT (1-845): 0: 1042: 98.34		PACN1_RAT (10-364): 2.01e-43: 157: 13.30
+	Hs
		1050712 DYN1_HUMAN (1-845): 0: 1050: 99.65		PACN1_HUMAN (2-364): 2.73e-36: 138: 12.40
+	Mm
		810542 DYN1_MOUSE (1-867): 0: 1086: 100.00		ITSN1_MOUSE (180-363): 1.24e-11: 68.1: 15.68
+	Mm
		810535 DYN1_MOUSE (1-867): 0: 1086: 100.00		SH3K1_MOUSE (288-364): 1.18e-11: 67.9: 22.08
+	Mm
		1223182 DYN3_MOUSE (1-839): 0: 991: 78.96		PACN1_MOUSE (10-364): 1.17e-43: 158: 13.02
+	Mm
		810548 DYN2_MOUSE (1-845): 0: 985: 78.28		PACN1_MOUSE (10-364): 1.17e-43: 158: 13.02
+	Mm
		810546 DYN2_MOUSE (1-845): 0: 985: 78.28		SRC8_MOUSE (20-363): 2.66e-40: 151: 14.49
+	Hs
		1050684 DYN1_HUMAN (1-845): 0: 1050: 99.65		ITSN1_HUMAN (180-363): 1.83e-11: 67.8: 15.68
+	Rn
		204807 DYN1_RAT (1-845): 0: 1042: 98.34		SRBS2_RAT (216-365): 2.86e-11: 67.1: 21.05
+	Rn
		638964 DYN1_RAT (1-845): 0: 1042: 98.34		ITSN1_RAT (180-363): 3.66e-11: 67: 16.22