HitPredict

Interactor 1: SH3G2 (Q99962)
Endophilin-A1 (EEN-B1) (Endophilin-1) (SH3 domain protein 2A) (SH3 domain-containing GRB2-like protein 2)
Gene: SH3GL2

Interactor 2: DYN3 (Q9UQ16)
Dynamin-3 (EC 3.6.5.5) (Dynamin, testicular) (T-dynamin)
Gene: DNM3

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	18602463
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005886 - plasma membrane GO:0048471 - perinuclear region of cytoplasm GO:0098793 - presynapse
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 352 Hs			1 869
+	Hs
		1408425 SH3G3_HUMAN (1-352): 2.72e-90: 276: 65.63		DYN3_HUMAN (1-869): 0: 1080: 100.00
+	Hs
		1408384 SH3G1_HUMAN (1-352): 9.12e-85: 262: 69.57		DYN3_HUMAN (1-869): 0: 1080: 100.00
+	Hs
		896872 SH3G2_HUMAN (1-352): 4.28e-96: 291: 100.00		DYN2_HUMAN (1-869): 0: 1041: 79.21
+	Hs
		1050711 SH3G2_HUMAN (1-352): 4.28e-96: 291: 100.00		DYN1_HUMAN (1-852): 0: 1035: 78.56
+	Mm
		810526 SH3G2_MOUSE (1-352): 2.57e-95: 289: 98.86		DYN1_MOUSE (1-847): 0: 1034: 78.90
+	Hs
		896873 SH3G3_HUMAN (1-352): 2.72e-90: 276: 65.63		DYN2_HUMAN (1-869): 0: 1041: 79.21
+	Rn
		204407 SH3G2_RAT (1-352): 1.56e-95: 289: 98.58		DYN1_RAT (1-852): 0: 1027: 78.22
+	Mm
		810527 SH3G3_MOUSE (1-351): 9e-91: 277: 64.67		DYN1_MOUSE (1-847): 0: 1034: 78.90
+	Hs
		896871 SH3G1_HUMAN (1-352): 9.12e-85: 262: 69.57		DYN2_HUMAN (1-869): 0: 1041: 79.21
+	Hs
		1050710 SH3G1_HUMAN (1-352): 9.12e-85: 262: 69.57		DYN1_HUMAN (1-852): 0: 1035: 78.56
+	Rn
		204411 SH3G3_RAT (1-352): 4.39e-88: 270: 65.91		DYN1_RAT (1-852): 0: 1027: 78.22
+	Mm
		810525 SH3G1_MOUSE (1-352): 6.12e-84: 260: 69.02		DYN1_MOUSE (1-847): 0: 1034: 78.90
+	Rn
		205730 SH3G1_RAT (1-352): 6.53e-84: 260: 69.57		DYN1_RAT (1-852): 0: 1027: 78.22
+	Mm
		810540 SHLB1_MOUSE (10-347): 1.08e-72: 231: 24.79		DYN1_MOUSE (1-847): 0: 1034: 78.90
+	Hs
		896753 SRC8_HUMAN (7-348): 2.97e-55: 191: 14.83		DYN2_HUMAN (1-869): 0: 1041: 79.21
+	Mm
		810546 SRC8_MOUSE (7-348): 8.94e-56: 192: 13.66		DYN2_MOUSE (1-869): 0: 1037: 79.21
+	Dm
		693527 SH3G3_DROME (1-352): 2.65e-74: 236: 47.43		DYN_DROME (6-861): 0: 974: 64.46
+	Ce
		73281 SH3GH_CAEEL (1-350): 8.61e-70: 224: 43.19		DYN1_CAEEL (3-815): 0: 946: 62.09
+	Hs
		135692 SH3G1_HUMAN (1-352): 9.12e-85: 262: 69.57		DNM1L_HUMAN (6-750): 0: 788: 38.25
+	Hs
		135709 SHLB2_HUMAN (10-347): 3.74e-62: 205: 21.35		DNM1L_HUMAN (6-750): 0: 788: 38.25