Interactor 1: SRBP1 (P36956)
Sterol regulatory element-binding protein 1 (SREBP-1) (Class D basic helix-loop-helix protein 1) (bHLHd1) (Sterol regulatory element-binding transcription factor 1) [Cleaved into: Processed sterol regulatory element-binding protein 1 (Transcription factor SREBF1)]
Gene: SREBF1

Interactor 2: SCAP (Q12770)
Sterol regulatory element-binding protein cleavage-activating protein (SCAP) (SREBP cleavage-activating protein)
Gene: SCAP

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.78 0.60 0.686

The method score is based on:

Property Details
Experiments 33156328, 29097707, 33961781, 9242699
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000139 - Golgi membrane
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0012507 - ER to Golgi transport vesicle membrane
GO:0032933 - SREBP signaling pathway
and 1 others

more...

Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 1147
Hs

1 1279
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+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024