HitPredict

Interactor 1: SRBP1 (P36956)
Sterol regulatory element-binding protein 1 (SREBP-1) (Class D basic helix-loop-helix protein 1) (bHLHd1) (Sterol regulatory element-binding transcription factor 1) [Cleaved into: Processed sterol regulatory element-binding protein 1 (Transcription factor SREBF1)]
Gene: SREBF1

Interactor 2: FBXW7 (Q969H0)
F-box/WD repeat-containing protein 7 (Archipelago homolog) (hAgo) (F-box and WD-40 domain-containing protein 7) (F-box protein FBX30) (SEL-10) (hCdc4)
Gene: FBXW7

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 0.60 0.753

The method score is based on:

Property Details
Experiments 26759235, 27579997, 32301540, 16825193, 19126544, 37052853, 16054087, 24298052
Identification Methods affinity chromatography technology, pull down, enzymatic study, unspecified method
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005783 - endoplasmic reticulum
GO:0005829 - cytosol
and 3 others

more...
Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 1147
Hs

1 707
+ Mm
+ Mm
+ Hs
+ Dm
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

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Last updated: 15 Jul 2024