HitPredict

Interactor 1: SOX5 (P35711)
Transcription factor SOX-5
Gene: SOX5

Interactor 2: PRC2A (P48634)
Protein PRRC2A (HLA-B-associated transcript 2) (Large proline-rich protein BAT2) (Proline-rich and coiled-coil-containing protein 2A) (Protein G2)
Gene: PRRC2A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.50	0.457

Property	Details
Experiments	35140242
Identification Methods	affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 763 Hs			1 2157
+	Hs
		776162 SOX6_HUMAN (14-763): 9.71e-145: 446: 56.21		PRC2A_HUMAN (1-2157): 2.13e-162: 555: 100.00
+	Hs
		776113 SOX5_HUMAN (1-763): 0: 611: 100.00		CIC_HUMAN (214-2122): 2.45e-25: 117: 9.87
+	Hs
		776155 SOX5_HUMAN (1-763): 0: 611: 100.00		PRC2C_HUMAN (256-2153): 5.31e-13: 77.4: 8.33
+	Hs
		161423 SOX5_HUMAN (1-763): 0: 611: 100.00		KMT2D_HUMAN (411-984): 2e-09: 65.4: 19.37
+	Hs
		776235 SOX6_HUMAN (14-763): 9.71e-145: 446: 56.21		CIC_HUMAN (214-2122): 2.45e-25: 117: 9.87
+	Hs
		776272 SOX6_HUMAN (14-763): 9.71e-145: 446: 56.21		PRC2C_HUMAN (256-2153): 5.31e-13: 77.4: 8.33
+	Hs
		872402 SOX2_HUMAN (520-642): 2.54e-36: 141: 38.10		PRC2B_HUMAN (1-2145): 3.28e-71: 268: 21.86
+	Hs
		169723 HGS_HUMAN (99-513): 2.29e-49: 188: 14.02		CIC_HUMAN (214-2122): 2.45e-25: 117: 9.87
+	Hs
		872506 SOX2_HUMAN (520-642): 2.54e-36: 141: 38.10		ANKH1_HUMAN (88-992): 3.87e-34: 146: 14.15
+	Hs
		873120 SOX9_HUMAN (463-700): 7.18e-45: 170: 26.86		CIC_HUMAN (214-2122): 2.45e-25: 117: 9.87
+	Hs
		872653 SOX2_HUMAN (520-642): 2.54e-36: 141: 38.10		CIC_HUMAN (214-2122): 2.45e-25: 117: 9.87
+	Hs
		873102 SOX9_HUMAN (463-700): 7.18e-45: 170: 26.86		KMT2C_HUMAN (660-2157): 9.75e-16: 86.3: 8.91
+	Mm
		107246 Q60I23_MOUSE (522-642): 3.91e-36: 140: 38.02		F8VQL9_MOUSE (14-1771): 1.42e-24: 115: 9.75
+	Hs
		872662 SOX2_HUMAN (520-642): 2.54e-36: 141: 38.10		MINT_HUMAN (2-1710): 1.45e-23: 112: 8.79
+	Hs
		872738 SOX2_HUMAN (520-642): 2.54e-36: 141: 38.10		TARA_HUMAN (719-2142): 1.18e-20: 102: 10.67
+	Hs
		161432 SOX9_HUMAN (463-700): 7.18e-45: 170: 26.86		KMT2D_HUMAN (411-984): 2e-09: 65.4: 19.37
+	Hs
		872546 SOX2_HUMAN (520-642): 2.54e-36: 141: 38.10		KMT2C_HUMAN (660-2157): 9.75e-16: 86.3: 8.91
+	Hs
		1338275 SOX17_HUMAN (517-720): 2.82e-34: 137: 30.81		KMT2C_HUMAN (660-2157): 9.75e-16: 86.3: 8.91
+	Hs
		161431 SOX2_HUMAN (520-642): 2.54e-36: 141: 38.10		KMT2D_HUMAN (411-984): 2e-09: 65.4: 19.37
+	Hs
		161514 SOX17_HUMAN (517-720): 2.82e-34: 137: 30.81		KMT2D_HUMAN (411-984): 2e-09: 65.4: 19.37