HitPredict

Interactor 1: ARL1 (P40616)
ADP-ribosylation factor-like protein 1
Gene: ARL1

Interactor 2: ARFG1 (Q8N6T3)
ADP-ribosylation factor GTPase-activating protein 1 (ARF GAP 1) (ADP-ribosylation factor 1 GTPase-activating protein) (ARF1 GAP) (ARF1-directed GTPase-activating protein)
Gene: ARFGAP1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	35844135
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Arf~ArfGap
Common GO terms	GO:0000139 - Golgi membrane GO:0005829 - cytosol GO:0016192 - vesicle-mediated transport GO:0046872 - metal ion binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 181 Hs			1 406
+	Hs
		950523 ARF1_HUMAN (1-181): 3.09e-68: 207: 56.91		ARFG1_HUMAN (1-406): 1.23e-119: 355: 100.00
+	Hs
		912911 ARF6_HUMAN (5-179): 4.77e-71: 214: 54.29		ACAP2_HUMAN (5-387): 3.03e-94: 301: 17.93
+	Hs
		897406 ARF3_HUMAN (1-181): 1.81e-68: 207: 56.91		ARFG3_HUMAN (1-404): 5.56e-75: 244: 21.13
+	Hs
		950563 ARF1_HUMAN (1-181): 3.09e-68: 207: 56.91		ARFG3_HUMAN (1-404): 5.56e-75: 244: 21.13
+	Hs
		574756 ARF4_HUMAN (1-180): 4.85e-68: 206: 58.33		ARFG3_HUMAN (1-404): 5.56e-75: 244: 21.13
+	Hs
		950718 ARF5_HUMAN (1-180): 6.4e-67: 203: 58.33		ARFG3_HUMAN (1-404): 5.56e-75: 244: 21.13
+	Hs
		897383 ARF3_HUMAN (1-181): 1.81e-68: 207: 56.91		ARFG2_HUMAN (3-404): 6.4e-73: 238: 18.88
+	Hs
		950522 ARF1_HUMAN (1-181): 3.09e-68: 207: 56.91		ARFG2_HUMAN (3-404): 6.4e-73: 238: 18.88
+	Hs
		574712 ARF4_HUMAN (1-180): 4.85e-68: 206: 58.33		ARFG2_HUMAN (3-404): 6.4e-73: 238: 18.88
+	Sc
		716034 ARL1_YEAST (1-181): 4.41e-80: 237: 63.74		GCS1_YEAST (3-332): 3.17e-62: 205: 25.47
+	Hs
		950654 ARF5_HUMAN (1-180): 6.4e-67: 203: 58.33		ARFG2_HUMAN (3-404): 6.4e-73: 238: 18.88
+	Hs
		912909 ARF6_HUMAN (5-179): 4.77e-71: 214: 54.29		ACAP1_HUMAN (9-384): 3.07e-62: 215: 12.93
+	Hs
		897390 ARF3_HUMAN (1-181): 1.81e-68: 207: 56.91		SMAP2_HUMAN (5-356): 1.14e-65: 217: 14.40
+	Hs
		574718 ARF4_HUMAN (1-180): 4.85e-68: 206: 58.33		SMAP2_HUMAN (5-356): 1.14e-65: 217: 14.40
+	At
		285978 ARF2B_ARATH (1-177): 2.26e-67: 204: 58.19		AGD7_ARATH (4-386): 2.81e-65: 217: 24.94
+	Sc
		503072 ARF1_YEAST (1-178): 6.27e-66: 201: 59.55		GCS1_YEAST (3-332): 3.17e-62: 205: 25.47
+	Sc
		744353 ARL1_YEAST (1-181): 4.41e-80: 237: 63.74		GLO3_YEAST (6-87): 6.22e-17: 84.3: 46.34
+	Sc
		580854 ARF2_YEAST (1-180): 9.78e-67: 203: 57.78		GLO3_YEAST (6-87): 6.22e-17: 84.3: 46.34
+	Hs
		913181 ARF6_HUMAN (5-179): 4.77e-71: 214: 54.29		ASAP1_HUMAN (6-89): 2.45e-12: 70.9: 38.10
+	Hs
		950577 ARF1_HUMAN (1-181): 3.09e-68: 207: 56.91		ASAP1_HUMAN (6-89): 2.45e-12: 70.9: 38.10