Interactor 1: RPN3 (P40016)
26S proteasome regulatory subunit RPN3
Gene: RPN3

Interactor 2: RPN7 (Q06103)
26S proteasome regulatory subunit RPN7
Gene: RPN7

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 1.00 0.979

The method score is based on:

Property Details
Experiments 11283351, 11742986, 16554755, 16429126, 18719252, 19446323, 24412063, 37968396, 31848235, 22195964, 22307589
Identification Methods two hybrid pooling approach, two hybrid, affinity chromatography technology, cross-linking study, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains PCI~PCI, PCI~RPN7, PCI~RPN7_PSMD6_C, RPN7_PSMD6_C~Rpn3_C
Common GO terms GO:0000502 - proteasome complex
GO:0006511 - ubiquitin-dependent protein catabolic process
GO:0008541 - proteasome regulatory particle, lid subcomplex
GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 523
Sc

1 429
+ Hs
+ Dm
+ Ce
+ Sc
+ Sp
+ Hs
+ Dm
+ Mm
+ Mm
+ Hs
+ Mm
+ Hs
+ Dm
+ At
+ Dm
+ At

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Last updated: 11Aug2025