HitPredict

Interactor 1: CLK2 (P49760)
Dual specificity protein kinase CLK2 (EC 2.7.12.1) (CDC-like kinase 2)
Gene: CLK2

Interactor 2: CE170 (Q5SW79)
Centrosomal protein of 170 kDa (Cep170) (KARP-1-binding protein) (KARP1-binding protein)
Gene: CEP170

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.80	0.514

Property	Details
Experiments	35709258
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	FHA~Pkinase
Common GO terms	-
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 499 Hs			1 1584
+	Hs
		1043852 DYR1A_HUMAN (108-485): 6.52e-105: 331: 28.50		CE170_HUMAN (1-1584): 0: 654: 100.00
+	Hs
		807687 CDK3_HUMAN (160-495): 1.29e-125: 370: 24.20		MAP1B_HUMAN (175-1557): 2.54e-45: 183: 9.56
+	Hs
		833993 CLK2_HUMAN (1-499): 1.97e-147: 432: 100.00		SRRM2_HUMAN (122-1517): 1.29e-18: 95.3: 9.74
+	Hs
		833836 CLK1_HUMAN (1-484): 3.66e-144: 424: 53.31		SRRM2_HUMAN (122-1517): 1.29e-18: 95.3: 9.74
+	Hs
		833803 CLK1_HUMAN (1-484): 3.66e-144: 424: 53.31		MINT_HUMAN (173-1570): 1.59e-17: 91.8: 7.72
+	Hs
		807717 DYR1A_HUMAN (108-485): 6.52e-105: 331: 28.50		MAP1B_HUMAN (175-1557): 2.54e-45: 183: 9.56
+	Hs
		834148 CLK3_HUMAN (1-499): 1.7e-136: 409: 59.32		SRRM2_HUMAN (122-1517): 1.29e-18: 95.3: 9.74
+	Hs
		625528 CDK2_HUMAN (160-488): 4.25e-133: 389: 24.70		TITIN_HUMAN (252-1467): 8.36e-24: 112: 8.68
+	Hs
		1335031 CLK4_HUMAN (1-484): 6.72e-136: 402: 55.05		SRRM2_HUMAN (122-1517): 1.29e-18: 95.3: 9.74
+	Hs
		944676 DYR1A_HUMAN (108-485): 6.52e-105: 331: 28.50		MAP1A_HUMAN (182-1393): 7.52e-37: 155: 10.27
+	Hs
		625642 CDK2_HUMAN (160-488): 4.25e-133: 389: 24.70		SRRM2_HUMAN (122-1517): 1.29e-18: 95.3: 9.74
+	Hs
		1268591 DYRK2_HUMAN (9-499): 1.04e-115: 355: 22.20		TARA_HUMAN (287-1532): 3.13e-27: 123: 8.21
+	Hs
		1264773 DYRK2_HUMAN (9-499): 1.04e-115: 355: 22.20		TITIN_HUMAN (252-1467): 8.36e-24: 112: 8.68
+	Hs
		1044147 DYR1A_HUMAN (108-485): 6.52e-105: 331: 28.50		TARA_HUMAN (287-1532): 3.13e-27: 123: 8.21
+	Ce
		246633 MBK2_CAEEL (145-487): 5.44e-111: 349: 27.93		O61201_CAEEL (255-1573): 1.24e-21: 105: 10.19
+	Hs
		1268608 DYRK2_HUMAN (9-499): 1.04e-115: 355: 22.20		SRRM2_HUMAN (122-1517): 1.29e-18: 95.3: 9.74
+	Dm
		830257 MNB_DROME (116-488): 9.19e-110: 348: 29.87		ELYS_DROME (342-1410): 8.95e-19: 95.6: 12.47
+	Hs
		1044321 DYR1A_HUMAN (108-485): 6.52e-105: 331: 28.50		PCLO_HUMAN (88-1566): 4.63e-11: 70.2: 9.45
+	Hs
		152642 DYR1A_HUMAN (108-485): 6.52e-105: 331: 28.50		KMT2D_HUMAN (119-1312): 8.58e-09: 62.9: 5.85