HitPredict

Interactor 1: GSK3B (P49841)
Glycogen synthase kinase-3 beta (GSK-3 beta) (EC 2.7.11.26) (Serine/threonine-protein kinase GSK3B) (EC 2.7.11.1)
Gene: GSK3B

Interactor 2: NBR1 (Q14596)
Next to BRCA1 gene 1 protein (Cell migration-inducing gene 19 protein) (Membrane component chromosome 17 surface marker 2) (Neighbor of BRCA1 gene 1 protein) (Protein 1A1-3B)
Gene: NBR1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.77	1.00	0.882

Property	Details
Experiments	29568061, 36779422, 24879152
Identification Methods	proximity labelling technology, enzymatic study, affinity chromatography technology, pull down, protein kinase assay
Interaction Type	physical association, direct interaction, phosphorylation reaction

Property	Details
Interacting Pfam domains	PB1~Pkinase
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0045668 - negative regulation of osteoblast differentiation
Homologous interactions	1

Homologous interactions

Color coding for hit scores

	1 420 Hs			1 966
+	Hs
		835372 GSK3A_HUMAN (21-420): 1.87e-147: 429: 77.75		NBR1_HUMAN (1-966): 0: 1811: 100.00