HitPredict

Interactor 1: IMA5 (P52294)
Importin subunit alpha-5 (Karyopherin subunit alpha-1) (Nucleoprotein interactor 1) (NPI-1) (RAG cohort protein 2) (SRP1-beta) [Cleaved into: Importin subunit alpha-5, N-terminally processed]
Gene: KPNA1

Interactor 2: NUP54 (Q7Z3B4)
Nucleoporin p54 (54 kDa nucleoporin)
Gene: NUP54

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	8707840
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005643 - nuclear pore GO:0006607 - NLS-bearing protein import into nucleus
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 538 Hs			1 507
+	Sc
		822992 IMA1_YEAST (2-538): 8.07e-143: 424: 49.26		NUP57_YEAST (3-489): 1.88e-59: 206: 18.52
+	Hs
		131388 IMA4_HUMAN (3-538): 1.73e-150: 443: 45.91		NU214_HUMAN (7-179): 1.39e-17: 88.5: 16.04
+	Hs
		238723 IMA7_HUMAN (1-538): 6.51e-160: 467: 80.48		P121A_HUMAN (2-189): 1.69e-09: 62.7: 18.78
+	Hs
		134948 IMA3_HUMAN (1-538): 7e-156: 456: 45.84		P121A_HUMAN (2-189): 1.69e-09: 62.7: 18.78
+	Hs
		131490 IMA4_HUMAN (3-538): 1.73e-150: 443: 45.91		P121A_HUMAN (2-189): 1.69e-09: 62.7: 18.78
+	Hs
		853423 IMA1_HUMAN (3-538): 1.64e-149: 441: 44.36		P121A_HUMAN (2-189): 1.69e-09: 62.7: 18.78
+	Sc
		971889 IMA1_YEAST (2-538): 8.07e-143: 424: 49.26		NU116_YEAST (5-265): 1.36e-12: 72.3: 13.51
+	Sc
		969354 IMA1_YEAST (2-538): 8.07e-143: 424: 49.26		NUP49_YEAST (6-267): 5.59e-11: 66.6: 11.28