HitPredict

Interactor 1: NSF (P46459)
Vesicle-fusing ATPase (EC 3.6.4.6) (N-ethylmaleimide-sensitive fusion protein) (NEM-sensitive fusion protein) (Vesicular-fusion protein NSF)
Gene: NSF

Interactor 2: PTN12 (Q05209)
Tyrosine-protein phosphatase non-receptor type 12 (EC 3.1.3.48) (PTP-PEST) (Protein-tyrosine phosphatase G1) (PTPG1)
Gene: PTPN12

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	19167335
Identification Methods	phosphatase assay
Interaction Type	dephosphorylation reaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 744 Hs			1 780
+	Hs
		471735 NSF_HUMAN (1-744): 0: 576: 100.00		PTPRC_HUMAN (13-677): 6.94e-141: 449: 19.62
+	Hs
		658815 NSF_HUMAN (1-744): 0: 576: 100.00		PTPRB_HUMAN (4-314): 9.8e-125: 413: 29.34
+	Mm
		204506 NSF_MOUSE (1-744): 0: 578: 98.12		PTN9_MOUSE (3-305): 2.65e-123: 383: 31.76
+	Rn
		1225421 NSF_RAT (1-744): 0: 576: 97.85		PTN9_RAT (3-305): 3.31e-123: 383: 31.76
+	Hs
		848988 NSF_HUMAN (1-744): 0: 576: 100.00		PTN9_HUMAN (3-305): 3.31e-123: 383: 32.08
+	Hs
		857110 NSF_HUMAN (1-744): 0: 576: 100.00		PTPRK_HUMAN (17-293): 1.38e-59: 221: 26.67
+	Hs
		659001 NSF_HUMAN (1-744): 0: 576: 100.00		PTPRG_HUMAN (8-325): 3.58e-53: 202: 23.33
+	Hs
		857117 NSF_HUMAN (1-744): 0: 576: 100.00		PTPRO_HUMAN (58-303): 3.33e-46: 180: 38.71
+	Hs
		857092 NSF_HUMAN (1-744): 0: 576: 100.00		PTPRJ_HUMAN (49-297): 6.26e-46: 179: 39.13
+	Hs
		935322 TERA_HUMAN (2-520): 3.85e-71: 250: 22.31		PTN22_HUMAN (1-779): 9.22e-129: 405: 32.61
+	Hs
		934511 TERA_HUMAN (2-520): 3.85e-71: 250: 22.31		PTN11_HUMAN (7-359): 5.77e-124: 385: 29.65
+	Hs
		848991 TERA_HUMAN (2-520): 3.85e-71: 250: 22.31		PTN9_HUMAN (3-305): 3.31e-123: 383: 32.08
+	Hs
		614672 TERA_HUMAN (2-520): 3.85e-71: 250: 22.31		PTPRA_HUMAN (7-295): 8.73e-105: 341: 32.08
+	Hs
		705693 TERA_HUMAN (2-520): 3.85e-71: 250: 22.31		PTPRM_HUMAN (7-293): 5.62e-62: 229: 24.75
+	Hs
		934938 TERA_HUMAN (2-520): 3.85e-71: 250: 22.31		PTPRU_HUMAN (2-293): 1.6e-59: 221: 21.33
+	Hs
		934685 TERA_HUMAN (2-520): 3.85e-71: 250: 22.31		PTPRO_HUMAN (58-303): 3.33e-46: 180: 38.71