Interactor 1: VPS4 (P52917)
Vacuolar protein sorting-associated protein 4 (DOA4-independent degradation protein 6) (Protein END13) (Vacuolar protein-targeting protein 10)
Gene: VPS4
Interactor 2: VTA1 (Q06263)
Vacuolar protein sorting-associated protein VTA1 (VPS20-associated protein 1)
Gene: VTA1
Species: Saccharomyces cerevisiae S288C
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.98 | 0.90 | 0.940 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 12953057, 20696398, 16601096, 15086794, 16193069, 16505166, 25164817, 17130288, 17408385, 18467557, 18719252, 18194651, 18032582, 16704411, 29165244, 28379137, 28714467, 18280501, 18266866, 24161953 |
| Identification Methods | affinity chromatography technology, x-ray crystallography, atpase assay, two hybrid, molecular sieving, surface plasmon resonance, pull down, biochemical, protein complementation assay, dihydrofolate reductase reconstruction |
| Interaction Type | direct interaction, association, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | AAA_lid_3~Vta1_C, Vps4_C~Vta1_C |
| Common GO terms | GO:0005768 - endosome GO:0015031 - protein transport GO:0032511 - late endosome to vacuole transport via multivesicular body sorting pathway GO:0045324 - late endosome to vacuole transport GO:1990621 - ESCRT IV complex |
| Homologous interactions | 0 |
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
