HitPredict

Interactor 1: PPP5 (P53041)
Serine/threonine-protein phosphatase 5 (PP5) (EC 3.1.3.16) (Protein phosphatase T) (PP-T) (PPT)
Gene: PPP5C

Interactor 2: CRY2 (Q49AN0)
Cryptochrome-2
Gene: CRY2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.614

Property	Details
Experiments	9383998, 16790549
Identification Methods	two hybrid, pull down, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 499 Hs			1 593
+	Rn
		858691 PPP5_RAT (1-499): 0: 572: 98.00		CRY2_RAT (18-593): 0: 793: 95.16
+	Hs
		858627 PPP5_HUMAN (1-499): 0: 575: 100.00		CRY1_HUMAN (21-524): 0: 678: 80.75
+	Hs
		915206 PP2AB_HUMAN (182-485): 6.26e-163: 465: 38.69		CRY2_HUMAN (18-593): 0: 781: 100.00
+	Rn
		858689 PPP5_RAT (1-499): 0: 572: 98.00		CRY1_RAT (21-524): 0: 673: 80.16
+	Hs
		915201 PP2AB_HUMAN (182-485): 6.26e-163: 465: 38.69		CRY1_HUMAN (21-524): 0: 678: 80.75
+	Hs
		905926 PP1A_HUMAN (200-479): 5.19e-154: 443: 38.79		CRY1_HUMAN (21-524): 0: 678: 80.75
+	Sc
		393886 PP2A1_YEAST (162-488): 6.84e-165: 472: 35.67		PHR_YEAST (22-506): 5.17e-131: 396: 23.21