HitPredict

Interactor 1: PPP5 (P53041)
Serine/threonine-protein phosphatase 5 (PP5) (EC 3.1.3.16) (Protein phosphatase T) (PP-T) (PPT)
Gene: PPP5C

Interactor 2: RBBP6 (Q7Z6E9)
E3 ubiquitin-protein ligase RBBP6 (EC 2.3.2.27) (Proliferation potential-related protein) (Protein P2P-R) (RING-type E3 ubiquitin transferase RBBP6) (Retinoblastoma-binding Q protein 1) (RBQ-1) (Retinoblastoma-binding protein 6) (p53-associated cellular protein of testis)
Gene: RBBP6

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	26496610
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005829 - cytosol GO:0032991 - protein-containing complex
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 499 Hs			1 1792
+	Hs
		110680 PPP5_HUMAN (1-499): 0: 575: 100.00		H3BSK8_HUMAN (134-1139): 1.9e-71: 263: 100.00
+	Dm
		1249943 Q8T0U6_DROME (144-479): 8.62e-163: 470: 34.22		Q9W3W6_DROME (309-1486): 5.87e-28: 126: 10.72
+	Hs
		930846 PP2AA_HUMAN (190-481): 5.28e-167: 475: 40.88		MDC1_HUMAN (508-1516): 4.61e-24: 113: 10.37
+	Dm
		1366837 Q9VH81_DROME (4-494): 8.41e-179: 513: 59.60		Q9VPR2_DROME (136-761): 2.66e-12: 74: 10.59
+	Dm
		1213568 Q9VH81_DROME (4-494): 8.41e-179: 513: 59.60		SLE_DROME (675-1778): 4.41e-12: 73.8: 10.19
+	Dm
		1366878 Q9VH81_DROME (4-494): 8.41e-179: 513: 59.60		Q9VU16_DROME (944-1569): 2.56e-11: 71.5: 16.94
+	Dm
		54887 Q9VH81_DROME (4-494): 8.41e-179: 513: 59.60		A1ZA72_DROME (910-1193): 5.51e-09: 63.8: 20.06
+	Dm
		819343 PP1B_DROME (196-484): 2.83e-150: 434: 37.24		Q9W3W6_DROME (309-1486): 5.87e-28: 126: 10.72
+	Sc
		696295 PP12_YEAST (196-479): 9.87e-151: 434: 39.65		MPE1_YEAST (2-378): 3.83e-29: 125: 26.03
+	Hs
		905894 PP1A_HUMAN (200-479): 5.19e-154: 443: 38.79		MDC1_HUMAN (508-1516): 4.61e-24: 113: 10.37
+	Dm
		113980 PP1B_DROME (196-484): 2.83e-150: 434: 37.24		M9PB30_DROME (259-1062): 5.51e-26: 120: 9.10
+	Hs
		230333 PP2AA_HUMAN (190-481): 5.28e-167: 475: 40.88		ZC3H1_HUMAN (679-1650): 2.57e-10: 68: 12.68
+	Dm
		54320 Q8T0U6_DROME (144-479): 8.62e-163: 470: 34.22		A1Z9J3_DROME (946-1383): 2.53e-11: 71.5: 15.33
+	Hs
		737948 PP1G_HUMAN (196-488): 1.79e-154: 444: 36.88		ELYS_HUMAN (577-1779): 2.2e-15: 84.9: 12.70
+	Hs
		906049 PP1A_HUMAN (200-479): 5.19e-154: 443: 38.79		ELYS_HUMAN (577-1779): 2.2e-15: 84.9: 12.70
+	Hs
		905838 PP1A_HUMAN (200-479): 5.19e-154: 443: 38.79		ANK2_HUMAN (331-1734): 6.96e-13: 76.5: 11.90
+	Hs
		230315 PP1G_HUMAN (196-488): 1.79e-154: 444: 36.88		ZC3H1_HUMAN (679-1650): 2.57e-10: 68: 12.68
+	Ce
		821920 GLC7B_CAEEL (196-485): 1.11e-154: 445: 38.49		MEL28_CAEEL (970-1774): 1.93e-09: 65.3: 14.81
+	Ce
		1090117 GLC7A_CAEEL (204-484): 5.64e-153: 440: 38.30		MEL28_CAEEL (970-1774): 1.93e-09: 65.3: 14.81