HitPredict

Interactor 1: RHOA (P61586)
Transforming protein RhoA (EC 3.6.5.2) (Rho cDNA clone 12) (h12)
Gene: RHOA

Interactor 2: ANR16 (Q6P6B7)
Ankyrin repeat domain-containing protein 16
Gene: ANKRD16

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Ank~Ras, Ank_2~Ras
Common GO terms	GO:0005634 - nucleus
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 193 Hs			1 361
+	Hs
		883465 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		RIPK4_HUMAN (4-303): 4.83e-72: 241: 29.04
+	Hs
		900896 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		Q9H4D1_HUMAN (8-303): 4.39e-67: 227: 29.77
+	Hs
		900423 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		ANK3_HUMAN (1-258): 1.9e-60: 212: 24.23
+	Hs
		925238 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		ANK3_HUMAN (1-258): 1.9e-60: 212: 24.23
+	Hs
		950953 RHOG_HUMAN (1-193): 2.83e-77: 231: 54.40		ANK3_HUMAN (1-258): 1.9e-60: 212: 24.23
+	Hs
		893947 CDC42_HUMAN (1-193): 5.51e-77: 230: 52.33		ANK3_HUMAN (1-258): 1.9e-60: 212: 24.23
+	Hs
		915638 RHOB_HUMAN (1-191): 1.62e-73: 221: 83.94		ANK3_HUMAN (1-258): 1.9e-60: 212: 24.23
+	Hs
		120412 RHOD_HUMAN (7-182): 1.68e-69: 212: 53.98		ANK3_HUMAN (1-258): 1.9e-60: 212: 24.23
+	Hs
		901042 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		KDIS_HUMAN (1-188): 1.14e-42: 160: 24.48
+	Hs
		925204 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		ANK2_HUMAN (1-156): 2.21e-43: 162: 26.58
+	Hs
		925723 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		KDIS_HUMAN (1-188): 1.14e-42: 160: 24.48
+	Hs
		436568 RHOC_HUMAN (1-193): 3.04e-78: 233: 91.71		KDIS_HUMAN (1-188): 1.14e-42: 160: 24.48
+	Hs
		951454 RHOG_HUMAN (1-193): 2.83e-77: 231: 54.40		KDIS_HUMAN (1-188): 1.14e-42: 160: 24.48
+	Hs
		894580 CDC42_HUMAN (1-193): 5.51e-77: 230: 52.33		KDIS_HUMAN (1-188): 1.14e-42: 160: 24.48
+	Hs
		545696 RAC2_HUMAN (1-193): 3.9e-76: 228: 53.61		KDIS_HUMAN (1-188): 1.14e-42: 160: 24.48
+	Hs
		892676 RAC3_HUMAN (1-179): 4.85e-74: 223: 57.54		KDIS_HUMAN (1-188): 1.14e-42: 160: 24.48
+	Hs
		916068 RHOB_HUMAN (1-191): 1.62e-73: 221: 83.94		KDIS_HUMAN (1-188): 1.14e-42: 160: 24.48
+	Hs
		120709 RHOD_HUMAN (7-182): 1.68e-69: 212: 53.98		KDIS_HUMAN (1-188): 1.14e-42: 160: 24.48