HitPredict

Interactor 1: SUMO2 (P61956)
Small ubiquitin-related modifier 2 (SUMO-2) (HSMT3) (SMT3 homolog 2) (SUMO-3) (Sentrin-2) (Ubiquitin-like protein SMT3B) (Smt3B)
Gene: SUMO2

Interactor 2: DAXX (Q9UER7)
Death domain-associated protein 6 (Daxx) (hDaxx) (ETS1-associated protein 1) (EAP1) (Fas death domain-associated protein)
Gene: DAXX

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.93	0.60	0.750

Property	Details
Experiments	22578841, 19394292, 32786267, 17081986, 28851805, 21383010, 16475184
Identification Methods	affinity chromatography technology, pull down, two hybrid, x-ray crystallography
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0016605 - PML body GO:0031625 - ubiquitin protein ligase binding
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 95 Hs			1 740
+	Hs
		879162 SUMO3_HUMAN (1-94): 3.76e-41: 132: 96.81		DAXX_HUMAN (1-740): 0: 1010: 100.00
+	Hs
		928220 SUMO1_HUMAN (1-93): 7.76e-35: 116: 45.36		DAXX_HUMAN (1-740): 0: 1010: 100.00
+	Mm
		193124 SUMO2_MOUSE (1-95): 3.56e-44: 139: 100.00		DAXX_MOUSE (1-740): 0: 953: 69.34
+	Mm
		193126 SUMO1_MOUSE (1-93): 7.76e-35: 116: 45.36		DAXX_MOUSE (1-740): 0: 953: 69.34
+	Dm
		332571 O97102_DROME (1-94): 1.24e-37: 123: 68.09		DAXX_DROME (95-407): 4.13e-104: 351: 27.99