Protein: RS4
Small ribosomal subunit protein uS4 (30S ribosomal protein S4)

Gene: RS4, rpsD
Organism: Escherichia coli K-12
Interactions: 236
UniProt ID: P0A7V8

Gene Ontology (top 5):
GO:0000028 - ribosomal small subunit assembly
GO:0000900 - mRNA regulatory element binding translation repressor activity
GO:0002181 - cytoplasmic translation
GO:0003735 - structural constituent of ribosome
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

462073

RS5
Small ribosomal subunit protein uS5

2

1

High-throughput

0.789

High

462106

RSUA
Ribosomal small subunit pseudouridine synthase A

2

3

High-throughput

0.759

High

462074

RS8
Small ribosomal subunit protein uS8

1

2

High-throughput

0.698

High

462093

CSPE
Cold shock-like protein CspE

3

5

High-throughput

0.657

High

462170

LPXD
UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase

3

3

High-throughput

0.657

High

462118

HSLR
Heat shock protein 15

1

0

High-throughput

0.656

High

459971

RPPH
RNA pyrophosphohydrolase

3

0

High-throughput

0.629

High

462138

NUSA
Transcription termination/antitermination protein NusA

3

0

High-throughput

0.629

High

462205

RLMN
Dual-specificity RNA methyltransferase RlmN

3

0

High-throughput

0.629

High

462105

RLUC
Ribosomal large subunit pseudouridine synthase C

1

3

High-throughput

0.625

High

462213

RLUB
Ribosomal large subunit pseudouridine synthase B

1

3

High-throughput

0.625

High

462196

RLUF
Dual-specificity RNA pseudouridine synthase RluF

1

2

High-throughput

0.618

High

462103

CSPA
Cold shock protein CspA

2

5

High-throughput

0.612

High

462104

CSPC
Cold shock-like protein CspC

2

5

High-throughput

0.612

High

462173

PSS
CDP-diacylglycerol--serine O-phosphatidyltransferase

3

0

High-throughput

0.607

High

462082

UVRC
UvrABC system protein C

2

1

High-throughput

0.601

High

462088

RPOC
DNA-directed RNA polymerase subunit beta'

1

0

High-throughput

0.593

High

393727

PNP
Polyribonucleotide nucleotidyltransferase

2

1

High-throughput

0.588

High

462085

RHLB
ATP-dependent RNA helicase RhlB

2

2

High-throughput

0.588

High

462162

SELB
Selenocysteine-specific elongation factor

2

1

High-throughput

0.588

High

458908

HFQ
RNA-binding protein Hfq

2

0

High-throughput

0.585

High

462077

RPOA
DNA-directed RNA polymerase subunit alpha

2

0

High-throughput

0.585

High

462256

DCYD
D-cysteine desulfhydrase

2

0

High-throughput

0.576

High

461887

RS3
Small ribosomal subunit protein uS3

1

1

High-throughput

0.575

High

462072

RS4
Small ribosomal subunit protein uS4

1

1

High-throughput

0.575

High

458968

IHFA
Integration host factor subunit alpha

2

3

High-throughput

0.570

High

459528

IF3
Translation initiation factor IF-3 [Cleaved into: Translation initiation factor IF-3, N-terminally processed; Translation initiation factor IF-3S]

2

0

High-throughput

0.563

High

462143

SPOT
Bifunctional

2

0

High-throughput

0.563

High

462149

SRP54
Signal recognition particle protein

2

0

High-throughput

0.563

High

462168

RNR
Ribonuclease R

2

0

High-throughput

0.563

High

462198

AIDB
Putative acyl-CoA dehydrogenase AidB

2

0

High-throughput

0.563

High

462202

CBPA
Curved DNA-binding protein

2

0

High-throughput

0.563

High

462230

RL4
Large ribosomal subunit protein uL4

2

0

High-throughput

0.563

High

459633

KPRS
Ribose-phosphate pyrophosphokinase

2

0

High-throughput

0.547

High

462150

SSB
Single-stranded DNA-binding protein

2

0

High-throughput

0.547

High

462153

YFIF
Uncharacterized tRNA/rRNA methyltransferase YfiF

2

0

High-throughput

0.545

High

462245

NPD
NAD-dependent protein deacylase

2

0

High-throughput

0.545

High

462232

FLAV
Flavodoxin 1

1

1

High-throughput

0.541

High

357017

RS7
Small ribosomal subunit protein uS7

1

2

High-throughput

0.536

High

459782

LPXA
Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase

1

3

High-throughput

0.536

High

461366

RS12
Small ribosomal subunit protein uS12

1

1

High-throughput

0.536

High

461397

RS13
Small ribosomal subunit protein uS13

1

2

High-throughput

0.536

High

461505

RS16
Small ribosomal subunit protein bS16

1

1

High-throughput

0.536

High

461604

RS19
Small ribosomal subunit protein uS19

1

2

High-throughput

0.536

High

462075

RS9
Small ribosomal subunit protein uS9

1

2

High-throughput

0.536

High

462094

CSPG
Cold shock-like protein CspG

1

5

High-throughput

0.536

High

462095

CSPI
Cold shock-like protein CspI

1

5

High-throughput

0.536

High

462098

RNG
Ribonuclease G

1

1

High-throughput

0.536

High

462114

GLMU
Bifunctional protein GlmU [Includes: UDP-N-acetylglucosamine pyrophosphorylase

1

1

High-throughput

0.536

High

462115

DBHA
DNA-binding protein HU-alpha

1

3

High-throughput

0.536

High

462116

DBHB
DNA-binding protein HU-beta

1

3

High-throughput

0.536

High

462129

RS15
Small ribosomal subunit protein uS15

1

1

High-throughput

0.536

High

462145

RS14
Small ribosomal subunit protein uS14

1

1

High-throughput

0.536

High

462146

RS1
Small ribosomal subunit protein bS1

1

1

High-throughput

0.536

High

462151

THIO2
Thioredoxin 2

1

1

High-throughput

0.536

High

462182

RHLE
ATP-dependent RNA helicase RhlE

1

2

High-throughput

0.536

High

343723

SYW
Tryptophan--tRNA ligase

1

0

High-throughput

0.513

High

381651

3MG2
DNA-3-methyladenine glycosylase 2

1

0

High-throughput

0.513

High

392888

EX7L
Exodeoxyribonuclease 7 large subunit

1

0

High-throughput

0.513

High

458747

FIS
DNA-binding protein Fis

1

0

High-throughput

0.513

High

460727

RL1
Large ribosomal subunit protein uL1

1

0

High-throughput

0.513

High

462084

RLMH
Ribosomal RNA large subunit methyltransferase H

1

0

High-throughput

0.513

High

462109

KBAY
D-tagatose-1,6-bisphosphate aldolase subunit KbaY

1

0

High-throughput

0.513

High

462113

GLRX4
Glutaredoxin 4

1

0

High-throughput

0.513

High

462117

STPA
DNA-binding protein StpA

1

0

High-throughput

0.513

High

462120

YMJA
Uncharacterized protein YmjA

1

0

High-throughput

0.513

High

462122

YEEZ
Protein YeeZ

1

0

High-throughput

0.513

High

462123

SUHB
Nus factor SuhB

1

0

High-throughput

0.513

High

462128

RL16
Large ribosomal subunit protein uL16

1

0

High-throughput

0.513

High

462140

YCFH
Uncharacterized metal-dependent hydrolase YcfH

1

0

High-throughput

0.513

High

462141

SSPB
Stringent starvation protein B

1

0

High-throughput

0.513

High

462144

RL17
Large ribosomal subunit protein bL17

1

0

High-throughput

0.513

High

462148

RPOE
ECF RNA polymerase sigma-E factor

1

0

High-throughput

0.513

High

462152

TRKA
Trk system potassium uptake protein TrkA

1

0

High-throughput

0.513

High

462155

RSME
Ribosomal RNA small subunit methyltransferase E

1

0

High-throughput

0.513

High

462164

MINC
Septum site-determining protein MinC

1

0

High-throughput

0.513

High

462175

FMT
Methionyl-tRNA formyltransferase

1

0

High-throughput

0.513

High

462177

INTD
Prophage integrase IntD

1

0

High-throughput

0.513

High

462178

RECG
ATP-dependent DNA helicase RecG

1

0

High-throughput

0.513

High

462184

PABC
Aminodeoxychorismate lyase

1

0

High-throughput

0.513

High

462185

FENR
Flavodoxin/ferredoxin--NADP reductase

1

0

High-throughput

0.513

High

462191

PANB
3-methyl-2-oxobutanoate hydroxymethyltransferase

1

0

High-throughput

0.513

High

462194

RHAD
Rhamnulose-1-phosphate aldolase

1

0

High-throughput

0.513

High

462204

RSMB
Ribosomal RNA small subunit methyltransferase B

1

0

High-throughput

0.513

High

462208

TAUD
Alpha-ketoglutarate-dependent taurine dioxygenase

1

0

High-throughput

0.513

High

462209

RLMJ
Ribosomal RNA large subunit methyltransferase J

1

0

High-throughput

0.513

High

462210

WAAF
Lipopolysaccharide heptosyltransferase 2

1

0

High-throughput

0.513

High

462214

YGGL
Uncharacterized protein YggL

1

0

High-throughput

0.513

High

462215

RSMC
Ribosomal RNA small subunit methyltransferase C

1

0

High-throughput

0.513

High

462216

ARFB
Peptidyl-tRNA hydrolase ArfB

1

0

High-throughput

0.513

High

462217

YHAK
Pirin-like protein YhaK

1

0

High-throughput

0.513

High

462218

OBG
GTPase ObgE/CgtA

1

0

High-throughput

0.513

High

462228

RL2
Large ribosomal subunit protein uL2

1

0

High-throughput

0.513

High

462229

UPPS
Ditrans,polycis-undecaprenyl-diphosphate synthase

1

0

High-throughput

0.513

High

462231

MDH
Malate dehydrogenase

1

0

High-throughput

0.513

High

462237

RSMI
Ribosomal RNA small subunit methyltransferase I

1

0

High-throughput

0.513

High

462240

GNGF
Putative gluconeogenesis factor

1

0

High-throughput

0.513

High

462242

RLMKL
Ribosomal RNA large subunit methyltransferase K/L [Includes: 23S rRNA m2G2445 methyltransferase

1

0

High-throughput

0.513

High

462258

MTFA
Mlc titration factor A

1

0

High-throughput

0.513

High

462125

YIHD
Protein YihD

1

0

High-throughput

0.493

High

340854

RPOD
RNA polymerase sigma factor RpoD

1

1

High-throughput

0.484

High

459002

IHFB
Integration host factor subunit beta

1

3

High-throughput

0.484

High

460012

NUSB
Transcription antitermination protein NusB

1

1

High-throughput

0.484

High

462092

CSPD
Cold shock-like protein CspD

1

5

High-throughput

0.484

High

462101

DEAD
ATP-dependent RNA helicase DeaD

1

1

High-throughput

0.484

High

462102

ULAR
HTH-type transcriptional regulator UlaR

1

1

High-throughput

0.484

High

462111

CLPA
ATP-dependent Clp protease ATP-binding subunit ClpA

1

1

High-throughput

0.484

High

462147

RPOH
RNA polymerase sigma factor RpoH

1

1

High-throughput

0.484

High

462169

RNE
Ribonuclease E

1

1

High-throughput

0.484

High

462107

YBCJ
Putative RNA-binding protein YbcJ

1

0

High-throughput

0.479

High

429392

FDHF
Formate dehydrogenase H

1

1

High-throughput

0.479

High

462091

RIMJ
[Ribosomal protein uS5]-alanine N-acetyltransferase

1

1

Small-scale

0.479

High

458712

FABZ
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ

1

0

High-throughput

0.464

High

459583

KDSA
2-dehydro-3-deoxyphosphooctonate aldolase

1

0

High-throughput

0.464

High

462099

PHOL
PhoH-like protein

1

0

High-throughput

0.464

High

462156

RLME
Ribosomal RNA large subunit methyltransferase E

1

0

High-throughput

0.464

High

462157

RCSB
Transcriptional regulatory protein RcsB

1

0

High-throughput

0.464

High

367364

PBPA
Penicillin-binding protein 1A

1

0

High-throughput

0.458

High

368563

DNAA
Chromosomal replication initiator protein DnaA

1

0

High-throughput

0.458

High

459893

NAGB
Glucosamine-6-phosphate deaminase

1

0

High-throughput

0.458

High

462086

YEEX
UPF0265 protein YeeX

1

0

High-throughput

0.458

High

462089

YFBU
UPF0304 protein YfbU

1

0

High-throughput

0.458

High

462110

PCNB
Poly(A) polymerase I

1

0

High-throughput

0.458

High

462154

YHBY
RNA-binding protein YhbY

1

0

High-throughput

0.458

High

462158

LPXB
Lipid-A-disaccharide synthase

1

0

High-throughput

0.458

High

462165

PARE
DNA topoisomerase 4 subunit B

1

0

High-throughput

0.458

High

462171

MUKB
Chromosome partition protein MukB

1

0

High-throughput

0.458

High

462172

ISPA
Farnesyl diphosphate synthase

1

0

High-throughput

0.458

High

462190

GLNE
Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme

1

0

High-throughput

0.458

High

462195

YJAG
Uncharacterized protein YjaG

1

0

High-throughput

0.458

High

462211

WBBJ
Putative lipopolysaccharide biosynthesis O-acetyl transferase WbbJ

1

0

High-throughput

0.458

High

462235

GMHBB
D-glycero-beta-D-manno-heptose-1,7-bisphosphate 7-phosphatase

1

0

High-throughput

0.458

High

462238

CSRA
Carbon storage regulator

1

0

High-throughput

0.458

High

459360

HSCA
Chaperone protein HscA

1

1

High-throughput

0.445

High

462263

HSCC
Chaperone protein HscC

1

3

High-throughput

0.445

High

462124

FIMB
Type 1 fimbriae regulatory protein FimB

1

1

High-throughput

0.442

High

448060

NARG
Respiratory nitrate reductase 1 alpha chain

1

1

High-throughput

0.437

High

421071

HIS2
Histidine biosynthesis bifunctional protein HisIE [Includes: Phosphoribosyl-AMP cyclohydrolase

1

0

High-throughput

0.426

High

461072

RL29
Large ribosomal subunit protein uL29

1

0

High-throughput

0.426

High

462079

TIG
Trigger factor

1

0

High-throughput

0.426

High

462080

YBEY
Endoribonuclease YbeY

1

0

High-throughput

0.426

High

462087

PRMA
Ribosomal protein L11 methyltransferase

1

0

High-throughput

0.426

High

462096

FTSZ
Cell division protein FtsZ

1

0

High-throughput

0.426

High

462097

SOXS
Regulatory protein SoxS

1

0

High-throughput

0.426

High

462100

SLYD
FKBP-type peptidyl-prolyl cis-trans isomerase SlyD

1

0

High-throughput

0.426

High

462121

YDJA
Putative NAD(P)H nitroreductase YdjA

1

0

High-throughput

0.426

High

462134

ELAB
Protein ElaB

1

0

High-throughput

0.426

High

462135

RIMO
Ribosomal protein uS12 methylthiotransferase RimO

1

0

High-throughput

0.426

High

462137

TSAE
tRNA threonylcarbamoyladenosine biosynthesis protein TsaE

1

0

High-throughput

0.426

High

462139

NUSG
Transcription termination/antitermination protein NusG

1

0

High-throughput

0.426

High

462161

RIML
Ribosomal-protein-serine acetyltransferase

1

0

High-throughput

0.426

High

462167

PNCA
Nicotinamidase

1

0

High-throughput

0.426

High

462181

MSYB
Acidic protein MsyB

1

0

High-throughput

0.426

High

462234

NFUA
Fe/S biogenesis protein NfuA

1

0

High-throughput

0.426

High

462267

ATOC
Regulatory protein AtoC

1

0

High-throughput

0.426

High

462112

FLAW
Flavodoxin 2

1

1

High-throughput

0.407

High

462250

YNAE
Uncharacterized protein YnaE

1

1

High-throughput

0.407

High

462253

YDFK
Cold shock protein YdfK

1

1

High-throughput

0.407

High

462266

YDJF
Uncharacterized HTH-type transcriptional regulator YdjF

1

1

High-throughput

0.407

High

462076

RNPA
Ribonuclease P protein component

2

0

High-throughput

0.319

High

462081

YACL
UPF0231 protein YacL

2

0

High-throughput

0.307

High

462200

NIKE
Nickel import ATP-binding protein NikE

2

0

High-throughput

0.307

High

462224

END8
Endonuclease 8

2

0

High-throughput

0.307

High

462241

YBJX
Uncharacterized protein YbjX

2

0

High-throughput

0.307

High

439011

YCIH
Uncharacterized protein YciH

1

0

High-throughput

0.279

Low

448110

YJAA
Uncharacterized protein YjaA

1

0

High-throughput

0.279

Low

462078

SFSA
Sugar fermentation stimulation protein A

1

0

High-throughput

0.279

Low

462108

YCGL
Protein YcgL

1

0

High-throughput

0.279

Low

462127

YGIC
Putative acid--amine ligase YgiC

1

0

High-throughput

0.279

Low

462131

DEGS
Serine endoprotease DegS

1

0

High-throughput

0.279

Low

462132

DMA
DNA adenine methylase

1

0

High-throughput

0.279

Low

462133

DSBC
Thiol:disulfide interchange protein DsbC

1

0

High-throughput

0.279

Low

462142

UBIX
Flavin prenyltransferase UbiX

1

0

High-throughput

0.279

Low

462159

DAMX
Cell division protein DamX

1

0

High-throughput

0.279

Low

462160

GLPD
Aerobic glycerol-3-phosphate dehydrogenase

1

0

High-throughput

0.279

Low

462163

MURG
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase

1

0

High-throughput

0.279

Low

462166

SPEA
Biosynthetic arginine decarboxylase

1

0

High-throughput

0.279

Low

462174

PRIC
Primosomal replication protein N''

1

0

High-throughput

0.279

Low

462176

MCRA
Type IV methyl-directed restriction enzyme EcoKMcrA

1

0

High-throughput

0.279

Low

462183

DING
ATP-dependent DNA helicase DinG

1

0

High-throughput

0.279

Low

462187

RIBX
N-glycosidase YbiA

1

0

High-throughput

0.279

Low

462193

CBRC
UPF0167 protein CbrC

1

0

High-throughput

0.279

Low

462197

NRFG
Formate-dependent nitrite reductase complex subunit NrfG

1

0

High-throughput

0.279

Low

462199

LLDD
L-lactate dehydrogenase

1

0

High-throughput

0.279

Low

462201

HOFQ
DNA utilization protein HofQ

1

0

High-throughput

0.279

Low

462206

YCHJ
UPF0225 protein YchJ

1

0

High-throughput

0.279

Low

462219

YHBQ
UPF0213 protein YhbQ

1

0

High-throughput

0.279

Low

462220

FKBA
FKBP-type peptidyl-prolyl cis-trans isomerase FkpA

1

0

High-throughput

0.279

Low

462221

YHFS
Uncharacterized protein YhfS

1

0

High-throughput

0.279

Low

462222

YHFX
Uncharacterized protein YhfX

1

0

High-throughput

0.279

Low

462223

RTCB
RNA-splicing ligase RtcB

1

0

High-throughput

0.279

Low

462225

RATB
UPF0125 protein RatB

1

0

High-throughput

0.279

Low

462226

FLIZ
Regulator of sigma S factor FliZ

1

0

High-throughput

0.279

Low

462239

WCAK
Colanic acid biosynthesis protein WcaK

1

0

High-throughput

0.279

Low

462244

THIK
Thiamine kinase

1

0

High-throughput

0.279

Low

462246

BLUR
HTH-type transcriptional repressor BluR

1

0

High-throughput

0.279

Low

462247

YCGM
Uncharacterized protein YcgM

1

0

High-throughput

0.279

Low

462252

YNEG
Uncharacterized protein YneG

1

0

High-throughput

0.279

Low

462255

YEAO
Uncharacterized protein YeaO

1

0

High-throughput

0.279

Low

462257

YEDK
Abasic site processing protein YedK

1

0

High-throughput

0.279

Low

462259

DSBG
Thiol:disulfide interchange protein DsbG

1

0

High-throughput

0.279

Low

462260

MURR
HTH-type transcriptional regulator MurR

1

0

High-throughput

0.279

Low

462261

EUTJ
Ethanolamine utilization protein EutJ

1

0

High-throughput

0.279

Low

462262

YGAV
Probable HTH-type transcriptional regulator YgaV

1

0

High-throughput

0.279

Low

462269

YAFO
mRNA interferase toxin YafO

1

0

High-throughput

0.279

Low

462270

YBCN
Uncharacterized protein YbcN

1

0

High-throughput

0.279

Low

462251

YDDJ
Putative protein YddJ

1

0

High-throughput

0.269

Low

462126

YGGE
Uncharacterized protein YggE

1

0

High-throughput

0.261

Low

460075

PLSB
Glycerol-3-phosphate acyltransferase

1

0

High-throughput

0.253

Low

462083

TRMB
tRNA

1

0

High-throughput

0.253

Low

462090

YBGC
Acyl-CoA thioester hydrolase YbgC

1

0

High-throughput

0.253

Low

462179

RIBD
Riboflavin biosynthesis protein RibD [Includes: Diaminohydroxyphosphoribosylaminopyrimidine deaminase

1

0

High-throughput

0.253

Low

462207

DCTR
HTH-type transcriptional regulator DctR

1

0

High-throughput

0.253

Low

462268

YGCP
Uncharacterized protein YgcP

1

0

High-throughput

0.253

Low

462180

YIDC
Membrane protein insertase YidC

1

0

Small-scale

0.249

Low

462186

LHR
Probable ATP-dependent helicase Lhr

1

0

High-throughput

0.249

Low

462192

POTF
Putrescine-binding periplasmic protein PotF

1

0

High-throughput

0.249

Low

462203

YADG
Uncharacterized ABC transporter ATP-binding protein YadG

1

0

High-throughput

0.249

Low

462212

WBBK
Putative glycosyltransferase WbbK

1

0

High-throughput

0.249

Low

462227

CSIE
Stationary phase-inducible protein CsiE

1

0

High-throughput

0.249

Low

462265

YBAY
Uncharacterized lipoprotein YbaY

1

0

High-throughput

0.249

Low

391293

NLPA
Lipoprotein 28

1

0

High-throughput

0.232

Low

421016

DICA
HTH-type transcriptional regulator DicA

1

0

High-throughput

0.232

Low

462119

SFSB
Sugar fermentation stimulation protein B

1

0

High-throughput

0.232

Low

462130

MAZE
Antitoxin MazE

1

0

High-throughput

0.232

Low

462136

ENTC
Isochorismate synthase EntC

1

0

High-throughput

0.232

Low

462188

INSZ
Putative transposase InsZ

1

0

High-throughput

0.232

Low

462189

PSUK
Pseudouridine kinase

1

0

High-throughput

0.232

Low

462233

ISPF
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase

1

0

High-throughput

0.232

Low

462236

YGHW
Uncharacterized protein YghW

1

0

High-throughput

0.232

Low

462243

SXY
Protein Sxy

1

0

High-throughput

0.232

Low

462248

YCJX
Ras-like GTPase YcjX

1

0

High-throughput

0.232

Low

462249

RACR
Prophage repressor RacR

1

0

High-throughput

0.232

Low

462254

YDFX
Protein YdfX

1

0

High-throughput

0.232

Low

462264

YDHW
Uncharacterized protein YdhW

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024