Interactor 1: GNAO (P51875)
Guanine nucleotide-binding protein G(o) subunit alpha
Gene: goa-1
Interactor 2: RIC8 (Q9GSX9)
Chaperone ric-8 (Resistance to inhibitors of cholinesterase protein 8) (Synembryn)
Gene: ric-8
Species: Caenorhabditis elegans
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.89 | 1.00 | 0.946 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 16162648, 15479639, 15498497, 15479638, 14704431 |
| Identification Methods | affinity chromatography technology, two hybrid, enzymatic study, biochemical, anti bait coimmunoprecipitation, gtpase assay, surface plasmon resonance, two hybrid pooling approach |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | G-alpha~Ric8 |
| Common GO terms | GO:0005737 - cytoplasm GO:0005938 - cell cortex GO:0007186 - G protein-coupled receptor signaling pathway GO:0060259 - regulation of feeding behavior |
| Homologous interactions | 12 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
