Protein: RIC8A
Chaperone Ric-8A (Synembryn-A)

Gene: RIC8A
Organism: Homo sapiens
Interactions: 88
UniProt ID: Q9NPQ8

Gene Ontology (top 5):
GO:0001701 - in utero embryonic development
GO:0001944 - vasculature development
GO:0001965 - G-protein alpha-subunit binding
GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

989882

GNAI1
Guanine nucleotide-binding protein G(i) subunit alpha-1

5

13

Small-scale

0.927

High

476042

GNAI3
Guanine nucleotide-binding protein G(i) subunit alpha-3

5

14

Small-scale

0.924

High

418747

GNAI2
Guanine nucleotide-binding protein G(i) subunit alpha-2

4

13

Small-scale

0.902

High

893526

GNAQ
Guanine nucleotide-binding protein G(q) subunit alpha

3

15

Small-scale

0.880

High

482641

GNAO
Guanine nucleotide-binding protein G(o) subunit alpha

2

13

Small-scale

0.808

High

1125934

GNA13
Guanine nucleotide-binding protein subunit alpha-13

2

14

Small-scale

0.808

High

1446620

UBQL1
Ubiquilin-1

5

1

High-throughput

0.728

High

1279981

NECA2
N-terminal EF-hand calcium-binding protein 2

1

0

High-throughput

0.702

High

618486

GNAZ
Guanine nucleotide-binding protein G(z) subunit alpha

1

13

High-throughput

0.691

High

716055

GNA11
Guanine nucleotide-binding protein subunit alpha-11

1

14

High-throughput

0.691

High

1040979

GNA12
Guanine nucleotide-binding protein subunit alpha-12

1

14

High-throughput

0.691

High

1446623

SHLB1
Endophilin-B1

3

1

High-throughput

0.660

High

140451

SDCB1
Syntenin-1

2

0

High-throughput

0.618

High

1294632

NUTM1
NUT family member 1

2

0

High-throughput

0.618

High

1446618

PRAF1
Prenylated Rab acceptor protein 1

2

0

High-throughput

0.618

High

1116947

AT1A4
Sodium/potassium-transporting ATPase subunit alpha-4

2

0

High-throughput

0.580

High

1400780

MYCT
Proton myo-inositol cotransporter

2

0

High-throughput

0.580

High

1446621

PACN2
Protein kinase C and casein kinase substrate in neurons protein 2

2

0

High-throughput

0.580

High

333215

VAPB
Vesicle-associated membrane protein-associated protein B/C

2

0

High-throughput

0.576

High

295636

CIB2
Calcium and integrin-binding family member 2

1

1

High-throughput

0.575

High

186587

TRI18
E3 ubiquitin-protein ligase Midline-1

1

1

Small-scale

0.561

High

243016

PRKN
E3 ubiquitin-protein ligase parkin

2

0

High-throughput

0.559

High

1446615

UBQL4
Ubiquilin-4

1

1

High-throughput

0.541

High

1446622

JIP3
C-Jun-amino-terminal kinase-interacting protein 3

1

1

High-throughput

0.541

High

837258

ACTY
Beta-centractin

1

1

High-throughput

0.536

High

958519

ACTZ
Alpha-centractin

1

1

High-throughput

0.536

High

1401171

SPAG5
Sperm-associated antigen 5

1

1

High-throughput

0.536

High

373227

MYC
Myc proto-oncogene protein

2

1

High-throughput

0.533

High

928557

TERF1
Telomeric repeat-binding factor 1

1

0

High-throughput

0.518

High

1118609

TBB2A
Tubulin beta-2A chain

1

0

High-throughput

0.518

High

1110731

DCTN2
Dynactin subunit 2

1

0

High-throughput

0.513

High

1123831

DCTN1
Dynactin subunit 1

1

0

High-throughput

0.513

High

1154452

STK11
Serine/threonine-protein kinase STK11

1

0

High-throughput

0.513

High

1403796

RMD3
Regulator of microtubule dynamics protein 3

1

0

High-throughput

0.513

High

1446619

DCTN4
Dynactin subunit 4

1

0

High-throughput

0.513

High

186047

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

1

High-throughput

0.501

High

562420

LAMP2
Lysosome-associated membrane glycoprotein 2

1

0

High-throughput

0.493

High

999414

HBB
Hemoglobin subunit beta

1

1

High-throughput

0.489

High

999688

HBA
Hemoglobin subunit alpha

1

1

High-throughput

0.489

High

1413449

DCTN5
Dynactin subunit 5

1

1

High-throughput

0.489

High

173410

XPO1
Exportin-1

1

1

High-throughput

0.481

High

1255663

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.479

High

1433971

PKHA4
Pleckstrin homology domain-containing family A member 4

1

1

High-throughput

0.479

High

223350

PRC1
Protein regulator of cytokinesis 1

1

0

High-throughput

0.458

High

343064

HERC2
E3 ubiquitin-protein ligase HERC2

1

0

High-throughput

0.458

High

412656

NTRK1
High affinity nerve growth factor receptor

1

0

High-throughput

0.458

High

696587

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

791751

SYUA
Alpha-synuclein

1

0

High-throughput

0.458

High

1067743

EP300
Histone acetyltransferase p300

1

0

High-throughput

0.458

High

1140904

KIF14
Kinesin-like protein KIF14

1

0

High-throughput

0.458

High

1249236

LMBRL
Protein LMBR1L

1

0

High-throughput

0.458

High

1380181

FBXW7
F-box/WD repeat-containing protein 7

1

0

High-throughput

0.458

High

1436492

ECT2
Protein ECT2

1

0

High-throughput

0.458

High

1446614

ANLN
Anillin

1

0

High-throughput

0.458

High

406685

MYCN
N-myc proto-oncogene protein

1

1

High-throughput

0.437

High

487782

PARP1
Poly [ADP-ribose] polymerase 1

1

1

High-throughput

0.437

High

731633

STIP1
Stress-induced-phosphoprotein 1

1

1

High-throughput

0.437

High

1100420

TIF1B
Transcription intermediary factor 1-beta

1

1

High-throughput

0.437

High

248947

GSDME
Gasdermin-E

1

0

High-throughput

0.426

High

260968

RAMP3
Receptor activity-modifying protein 3

1

0

High-throughput

0.426

High

397983

ANGI
Angiogenin

1

0

High-throughput

0.426

High

466975

ACM4
Muscarinic acetylcholine receptor M4

1

0

High-throughput

0.426

High

854585

S15A1
Solute carrier family 15 member 1

1

0

High-throughput

0.426

High

1209691

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

0

High-throughput

0.426

High

1290494

IQGA3
Ras GTPase-activating-like protein IQGAP3

1

0

High-throughput

0.426

High

1366254

LPAR1
Lysophosphatidic acid receptor 1

1

0

High-throughput

0.426

High

1086446

FBLN3
EGF-containing fibulin-like extracellular matrix protein 1

3

0

High-throughput

0.352

High

1198154

Z585B
Zinc finger protein 585B

1

0

High-throughput

0.282

High

1307652

ZDH17
Palmitoyltransferase ZDHHC17

1

0

High-throughput

0.282

High

133381

DCTN6
Dynactin subunit 6

1

0

High-throughput

0.279

Low

298231

DCTN3
Dynactin subunit 3

1

0

High-throughput

0.279

Low

854324

KI67
Proliferation marker protein Ki-67

1

0

High-throughput

0.279

Low

1329736

ARFG1
ADP-ribosylation factor GTPase-activating protein 1

1

0

High-throughput

0.279

Low

1446616

ARP10
Actin-related protein 10

1

0

High-throughput

0.279

Low

1446617

MTCH1
Mitochondrial carrier homolog 1

1

0

High-throughput

0.279

Low

106691

APRIO
Alternative prion protein

1

0

High-throughput

0.249

Low

157884

CTRO
Citron Rho-interacting kinase

1

0

High-throughput

0.249

Low

342331

BRD1
Bromodomain-containing protein 1

1

0

High-throughput

0.249

Low

589771

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.249

Low

769257

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low

1178400

CL16A
Protein CLEC16A

1

0

High-throughput

0.249

Low

1276826

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.249

Low

1391783

AURKB
Aurora kinase B

1

0

High-throughput

0.249

Low

1134

SIM26
Small integral membrane protein 26

1

0

High-throughput

0.232

Low

628466

KLK2
Kallikrein-2

1

0

High-throughput

0.232

Low

1185903

TMM95
Sperm-egg fusion protein TMEM95

1

0

High-throughput

0.232

Low

1208283

SPXN3
Sperm protein associated with the nucleus on the X chromosome N3

1

0

High-throughput

0.232

Low

1239305

ARMC6
Armadillo repeat-containing protein 6

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025