Protein: TM165
Putative divalent cation/proton antiporter TMEM165 (Transmembrane protein 165) (Transmembrane protein PT27) (Transmembrane protein TPARL)

Gene: TM165, TMEM165
Organism: Homo sapiens
Interactions: 84
UniProt ID: Q9HC07

Gene Ontology (top 5):
GO:0000139 - Golgi membrane
GO:0005384 - manganese ion transmembrane transporter activity
GO:0005765 - lysosomal membrane
GO:0005794 - Golgi apparatus
GO:0006487 - protein N-linked glycosylation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1042580

CUL3
Cullin-3

2

0

High-throughput

0.585

High

1295811

S35E1
Solute carrier family 35 member E1

1

1

High-throughput

0.536

High

331671

B3GT4
Beta-1,3-galactosyltransferase 4

1

0

High-throughput

0.513

High

529744

CFTR
Cystic fibrosis transmembrane conductance regulator

1

0

High-throughput

0.513

High

848486

IRAK1
Interleukin-1 receptor-associated kinase 1

1

0

High-throughput

0.513

High

1027570

STX5
Syntaxin-5

1

0

High-throughput

0.513

High

1139000

GP107
Protein GPR107

1

0

High-throughput

0.513

High

1253899

SPP2B
Signal peptide peptidase-like 2B

1

0

High-throughput

0.513

High

1333925

GORS2
Golgi reassembly-stacking protein 2

1

0

High-throughput

0.513

High

1191382

ADCK2
Uncharacterized aarF domain-containing protein kinase 2

1

1

High-throughput

0.489

High

1287846

COQ8B
Atypical kinase COQ8B, mitochondrial

1

1

High-throughput

0.489

High

1302133

SMC6
Structural maintenance of chromosomes protein 6

1

1

High-throughput

0.489

High

348934

RASN
GTPase NRas

1

3

High-throughput

0.479

High

349659

RASH
GTPase HRas

1

2

High-throughput

0.479

High

350569

RASK
GTPase KRas

1

3

High-throughput

0.479

High

1269664

ESR2
Estrogen receptor beta

1

1

High-throughput

0.479

High

1335656

AMFR
E3 ubiquitin-protein ligase AMFR

1

1

High-throughput

0.479

High

127055

PDE2A
cGMP-dependent 3',5'-cyclic phosphodiesterase

1

0

High-throughput

0.458

High

132599

RCAS1
Receptor-binding cancer antigen expressed on SiSo cells

1

0

High-throughput

0.458

High

206008

TGON2
Trans-Golgi network integral membrane protein 2

1

0

High-throughput

0.458

High

545041

AMPN
Aminopeptidase N

1

0

High-throughput

0.458

High

648892

DPP4
Dipeptidyl peptidase 4

1

0

High-throughput

0.458

High

844748

RAB5C
Ras-related protein Rab-5C

1

0

High-throughput

0.458

High

895280

RAB2A
Ras-related protein Rab-2A

1

0

High-throughput

0.458

High

1101302

CL16A
Protein CLEC16A

1

0

High-throughput

0.458

High

1220989

FA20C
Extracellular serine/threonine protein kinase FAM20C

1

0

High-throughput

0.458

High

1284241

CLUA1
Clusterin-associated protein 1

1

0

High-throughput

0.458

High

1335652

B3GA1
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1

1

0

High-throughput

0.458

High

1335653

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

1335658

TRRAP
Transformation/transcription domain-associated protein

1

0

High-throughput

0.458

High

1314483

IFT27
Intraflagellar transport protein 27 homolog

1

1

High-throughput

0.445

High

377697

GCR
Glucocorticoid receptor

1

1

High-throughput

0.437

High

1259709

RN139
E3 ubiquitin-protein ligase RNF139

1

2

High-throughput

0.437

High

1327655

BRD8
Bromodomain-containing protein 8

1

1

High-throughput

0.437

High

981731

REL
Proto-oncogene c-Rel

1

0

High-throughput

0.282

High

1335650

AHSP
Alpha-hemoglobin-stabilizing protein

1

0

High-throughput

0.282

High

146870

CDKA1
Cyclin-dependent kinase 2-associated protein 1

1

0

High-throughput

0.279

Low

156935

FFAR1
Free fatty acid receptor 1

1

0

High-throughput

0.279

Low

172232

GP182
G-protein coupled receptor 182

1

0

High-throughput

0.279

Low

415073

CDK1
Cyclin-dependent kinase 1

1

0

High-throughput

0.279

Low

792855

EAA3
Excitatory amino acid transporter 3

1

0

High-throughput

0.279

Low

1033565

ILK
Integrin-linked protein kinase

1

0

High-throughput

0.279

Low

1085511

MK06
Mitogen-activated protein kinase 6

1

0

High-throughput

0.279

Low

1153744

STYK1
Tyrosine-protein kinase STYK1

1

0

High-throughput

0.279

Low

1174187

UBP43
Ubiquitin carboxyl-terminal hydrolase 43

1

0

High-throughput

0.279

Low

1204520

VSIG1
V-set and immunoglobulin domain-containing protein 1

1

0

High-throughput

0.279

Low

1332016

SG196
Protein O-mannose kinase

1

0

High-throughput

0.279

Low

1335648

NRBP2
Nuclear receptor-binding protein 2

1

0

High-throughput

0.279

Low

1335651

CNOT2
CCR4-NOT transcription complex subunit 2

1

0

High-throughput

0.279

Low

1335655

GPTC8
G patch domain-containing protein 8

1

0

High-throughput

0.279

Low

1335657

SMC3
Structural maintenance of chromosomes protein 3

1

0

High-throughput

0.279

Low

1198179

TM11B
Transmembrane protease serine 11B

1

0

High-throughput

0.269

Low

1335654

ERRFI
ERBB receptor feedback inhibitor 1

1

0

Small-scale

0.251

Low

116714

UBXN8
UBX domain-containing protein 8

1

0

High-throughput

0.249

Low

164483

TRI66
Tripartite motif-containing protein 66

1

0

High-throughput

0.249

Low

387548

P53
Cellular tumor antigen p53

1

0

High-throughput

0.249

Low

525647

COX41
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial

1

0

High-throughput

0.249

Low

553766

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.249

Low

719160

PHB1
Prohibitin 1

1

0

High-throughput

0.249

Low

721495

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low

780134

CCNF
Cyclin-F

1

0

High-throughput

0.249

Low

824403

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

0

High-throughput

0.249

Low

828024

UB2R1
Ubiquitin-conjugating enzyme E2 R1

1

0

High-throughput

0.249

Low

941451

RNF4
E3 ubiquitin-protein ligase RNF4

1

0

High-throughput

0.249

Low

947860

KGD4
Alpha-ketoglutarate dehydrogenase component 4

1

0

High-throughput

0.249

Low

1086798

CLPP
ATP-dependent Clp protease proteolytic subunit, mitochondrial

1

0

High-throughput

0.249

Low

1088075

DUS7
Dual specificity protein phosphatase 7

1

0

High-throughput

0.249

Low

1124459

TM41B
Transmembrane protein 41B

1

0

High-throughput

0.249

Low

1138631

OTUD1
OTU domain-containing protein 1

1

0

Small-scale

0.249

Low

1148796

VIR
Protein virilizer homolog

1

0

High-throughput

0.249

Low

1165967

LMBRL
Protein LMBR1L

1

0

High-throughput

0.249

Low

1171789

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

1188890

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.249

Low

1230381

CXD3
Gap junction delta-3 protein

1

0

High-throughput

0.249

Low

1233454

NIN
Ninein

1

0

High-throughput

0.249

Low

1327105

SPRTN
DNA-dependent metalloprotease SPRTN

1

0

High-throughput

0.249

Low

1331336

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.249

Low

1332631

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.249

Low

1335033

PRD16
Histone-lysine N-methyltransferase PRDM16

1

0

High-throughput

0.249

Low

1335495

NMRL1
NmrA-like family domain-containing protein 1

1

0

High-throughput

0.249

Low

1335649

ELOV5
Very long chain fatty acid elongase 5

1

0

High-throughput

0.249

Low

204561

PROM1
Prominin-1

1

0

Small-scale

0.238

Low

1133

SIM26
Small integral membrane protein 26

1

0

High-throughput

0.232

Low

1329430

S38A1
Sodium-coupled neutral amino acid symporter 1

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024