HitPredict

Interactor 1: 1433E (P62258)
14-3-3 protein epsilon (14-3-3E)
Gene: YWHAE

Interactor 2: LRCH1 (Q9Y2L9)
Leucine-rich repeat and calponin homology domain-containing protein 1 (Calponin homology domain-containing protein 1) (Neuronal protein 81) (NP81)
Gene: LRCH1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.70	0.60	0.650

Property	Details
Experiments	31980649, 35271311, unassigned2173
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 255 Hs			1 728
+	Mm
		910293 1433E_MOUSE (1-255): 4.87e-154: 430: 100.00		LRCH3_MOUSE (60-691): 7.12e-93: 307: 37.88
+	Zm
		22560 B6U284_MAIZE (3-255): 8.23e-147: 412: 70.59		A0A1D6I257_MAIZE (1-507): 3.4e-67: 241: 14.45
+	Hs
		909939 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		ERBIN_HUMAN (123-615): 2.73e-37: 152: 16.37
+	Hs
		910166 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		SHOC2_HUMAN (61-184): 7.76e-21: 99.1: 29.37
+	Mm
		910240 1433E_MOUSE (1-255): 4.87e-154: 430: 100.00		LRCH2_MOUSE (6-191): 2.11e-19: 95.2: 14.85
+	At
		965375 14332_ARATH (4-255): 1.05e-147: 414: 74.41		BRL2_ARATH (5-280): 2.02e-23: 108: 19.45
+	At
		788683 14333_ARATH (1-253): 3.45e-147: 413: 74.12		BRL2_ARATH (5-280): 2.02e-23: 108: 19.45
+	At
		788640 14333_ARATH (1-253): 3.45e-147: 413: 74.12		EMS1_ARATH (428-637): 7.33e-23: 106: 11.31
+	At
		788442 14331_ARATH (4-245): 3.88e-144: 405: 75.41		EMS1_ARATH (428-637): 7.33e-23: 106: 11.31
+	At
		965369 14332_ARATH (4-255): 1.05e-147: 414: 74.41		CLV1_ARATH (4-134): 9.08e-15: 80.5: 14.29