HitPredict

Interactor 1: RHOB (P62745)
Rho-related GTP-binding protein RhoB (Rho cDNA clone 6) (h6)
Gene: RHOB

Interactor 2: ROBO1 (Q9Y6N7)
Roundabout homolog 1 (Deleted in U twenty twenty) (H-Robo-1)
Gene: ROBO1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	34079125, 31871319
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ras~fn3
Common GO terms	GO:0005886 - plasma membrane GO:0007155 - cell adhesion GO:0030336 - negative regulation of cell migration
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 196 Hs			1 1651
+	Hs
		915881 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		NEO1_HUMAN (1-1369): 7.12e-102: 361: 16.01
+	Hs
		564637 RHOQ_HUMAN (2-195): 6.71e-68: 207: 51.74		NEO1_HUMAN (1-1369): 7.12e-102: 361: 16.01
+	Hs
		915989 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		ROBO2_HUMAN (1-1338): 5.28e-93: 333: 16.74
+	Hs
		925776 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		ROBO1_HUMAN (1-673): 4.35e-68: 256: 18.79
+	Hs
		901110 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		ROBO1_HUMAN (1-673): 4.35e-68: 256: 18.79
+	Hs
		436602 RHOC_HUMAN (1-196): 8.84e-76: 227: 83.16		ROBO1_HUMAN (1-673): 4.35e-68: 256: 18.79
+	Hs
		894644 CDC42_HUMAN (1-196): 1.35e-74: 224: 49.49		ROBO1_HUMAN (1-673): 4.35e-68: 256: 18.79
+	Hs
		564764 RHOQ_HUMAN (2-195): 6.71e-68: 207: 51.74		ROBO1_HUMAN (1-673): 4.35e-68: 256: 18.79
+	Hs
		915725 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		SDK2_HUMAN (335-1452): 4.76e-41: 168: 11.39
+	Hs
		900635 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		SDK1_HUMAN (160-796): 6.64e-19: 96.1: 13.32
+	Hs
		915792 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		SDK1_HUMAN (160-796): 6.64e-19: 96.1: 13.32
+	Hs
		894276 CDC42_HUMAN (1-196): 1.35e-74: 224: 49.49		PXDN_HUMAN (338-543): 2.3e-19: 97.4: 33.18