HitPredict

Interactor 1: JAG1 (P78504)
Protein jagged-1 (Jagged1) (hJ1) (CD antigen CD339)
Gene: JAG1

Interactor 2: FBX2 (Q9UK22)
F-box only protein 2
Gene: FBXO2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 1218 Hs			1 296
+	Hs
		1356246 JAG2_HUMAN (26-1132): 2.03e-162: 518: 54.42		FBX2_HUMAN (1-296): 5.13e-147: 416: 100.00
+	Hs
		624336 TENA_HUMAN (36-485): 7.44e-57: 219: 21.09		FBX6_HUMAN (40-296): 2.4e-133: 381: 49.81
+	Hs
		980571 NOTC2_HUMAN (591-1041): 2.37e-45: 182: 24.42		FBX2_HUMAN (1-296): 5.13e-147: 416: 100.00
+	Hs
		804367 NOTC1_HUMAN (22-654): 1.13e-44: 179: 20.73		FBX2_HUMAN (1-296): 5.13e-147: 416: 100.00
+	Hs
		1356241 NOTC3_HUMAN (637-1062): 5.33e-38: 158: 23.71		FBX2_HUMAN (1-296): 5.13e-147: 416: 100.00
+	Hs
		724359 FBN1_HUMAN (208-1038): 2.5e-27: 123: 17.84		FBX2_HUMAN (1-296): 5.13e-147: 416: 100.00
+	Hs
		1350098 TEN3_HUMAN (819-1027): 5.71e-25: 115: 12.15		FBX2_HUMAN (1-296): 5.13e-147: 416: 100.00
+	Hs
		1256715 SNED1_HUMAN (760-1047): 3.22e-13: 76.9: 17.04		FBX2_HUMAN (1-296): 5.13e-147: 416: 100.00
+	Hs
		1204965 FRAS1_HUMAN (588-1026): 1.05e-09: 65.3: 11.14		FBX2_HUMAN (1-296): 5.13e-147: 416: 100.00
+	Hs
		724399 FBN2_HUMAN (505-1046): 1.1e-09: 65.3: 14.16		FBX2_HUMAN (1-296): 5.13e-147: 416: 100.00
+	Hs
		1204960 FRAS1_HUMAN (588-1026): 1.05e-09: 65.3: 11.14		FBX6_HUMAN (40-296): 2.4e-133: 381: 49.81
+	Hs
		724395 FBN2_HUMAN (505-1046): 1.1e-09: 65.3: 14.16		FBX6_HUMAN (40-296): 2.4e-133: 381: 49.81