HitPredict

Interactor 1: E7DN81 (E7DN81)
DNA-directed DNA polymerase (EC 2.7.7.7)
Gene: E7DN81

Interactor 2: E7DN81 (E7DN81)
DNA-directed DNA polymerase (EC 2.7.7.7)
Gene: E7DN81

Species: Streptococcus phage Dp-1

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.34	1.00	0.590

Property	Details
Experiments	21097633
Identification Methods	two hybrid array
Interaction Type	physical association

Property	Details
Interacting Pfam domains	DNA_pol3_delta2~DNA_pol3_delta2, DNA_pol3_delta2~DNA_pol3_gamma3, DNA_pol3_gamma3~DNA_pol3_gamma3
Common GO terms	GO:0003677 - DNA binding GO:0003887 - DNA-directed DNA polymerase activity GO:0005524 - ATP binding GO:0006261 - DNA-templated DNA replication GO:0009360 - DNA polymerase III complex and 1 others more... GO:0016887 - ATP hydrolysis activity
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 341 Sp			1 341
+	Cj
		1076087 Q0P999_CAMJE (2-300): 1.51e-77: 248: 33.02		Q0P999_CAMJE (2-300): 1.51e-77: 248: 33.02
+	Mm
		1317153 AFG32_MOUSE (10-340): 6.85e-69: 231: 12.40		AFG32_MOUSE (10-340): 6.85e-69: 231: 12.40
+	Mm
		1317154 AFG32_MOUSE (10-340): 6.85e-69: 231: 12.40		AFG31_MOUSE (10-340): 3.71e-68: 229: 13.16
+	Ec
		445391 DPO3X_ECOLI (3-336): 5.96e-69: 229: 32.87		DPO3X_ECOLI (3-336): 5.96e-69: 229: 32.87
+	Hs
		769669 RFC4_HUMAN (1-309): 5.7e-72: 229: 22.22		RFC5_HUMAN (1-317): 1.96e-71: 227: 22.29
+	Hs
		769666 RFC4_HUMAN (1-309): 5.7e-72: 229: 22.22		RFC2_HUMAN (1-312): 2.04e-70: 225: 22.98
+	Hs
		769818 RFC5_HUMAN (1-317): 1.96e-71: 227: 22.29		RFC2_HUMAN (1-312): 2.04e-70: 225: 22.98
+	At
		1373692 RFC4_ARATH (2-320): 1.25e-74: 235: 24.41		RFC5_ARATH (2-314): 1.91e-63: 207: 20.73
+	Zm
		78939 B4FQT5_MAIZE (2-324): 2.02e-69: 221: 22.02		B4FJC2_MAIZE (2-317): 1.46e-67: 218: 24.07
+	Tp
		311950 O83970_TREPA (6-338): 1.1e-65: 218: 27.70		O83970_TREPA (6-338): 1.1e-65: 218: 27.70
+	At
		1423462 RFC2_ARATH (2-318): 5.6e-70: 223: 21.43		RFC5_ARATH (2-314): 1.91e-63: 207: 20.73
+	Hs
		769670 RFC4_HUMAN (1-309): 5.7e-72: 229: 22.22		RFC3_HUMAN (3-319): 6.85e-60: 197: 15.86
+	Hs
		829043 RFC5_HUMAN (1-317): 1.96e-71: 227: 22.29		RFC3_HUMAN (3-319): 6.85e-60: 197: 15.86
+	Hs
		769819 RFC2_HUMAN (1-312): 2.04e-70: 225: 22.98		RFC3_HUMAN (3-319): 6.85e-60: 197: 15.86
+	Sc
		800950 RFC3_YEAST (1-318): 1.04e-67: 217: 21.58		RFC4_YEAST (1-317): 3.41e-62: 203: 21.58