HitPredict

Interactor 1: DCAF7 (P61962)
DDB1- and CUL4-associated factor 7 (WD repeat-containing protein 68) (WD repeat-containing protein An11 homolog)
Gene: DCAF7

Interactor 2: CIC (Q96RK0)
Protein capicua homolog
Gene: CIC

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29844126
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0032991 - protein-containing complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 342 Hs			1 2517
+	Hs
		965173 WDR5_HUMAN (208-342): 1.41e-28: 114: 11.85		CIC_HUMAN (1-2517): 0: 945: 100.00
+	Hs
		1158968 RBBP7_HUMAN (2-153): 4.87e-15: 77.5: 15.72		CIC_HUMAN (1-2517): 0: 945: 100.00
+	Hs
		872147 DCAF7_HUMAN (1-342): 2.52e-86: 265: 100.00		SOX2_HUMAN (1073-1308): 2.24e-57: 204: 24.05
+	Hs
		776167 DCAF7_HUMAN (1-342): 2.52e-86: 265: 100.00		SOX6_HUMAN (887-1289): 3.78e-35: 148: 16.28
+	Hs
		776041 DCAF7_HUMAN (1-342): 2.52e-86: 265: 100.00		SOX5_HUMAN (1097-1211): 1.92e-34: 146: 28.70
+	Hs
		964775 DCAF7_HUMAN (1-342): 2.52e-86: 265: 100.00		SRRM2_HUMAN (850-2517): 1.87e-29: 131: 7.91
+	Mm
		1222141 TBL1R_MOUSE (66-254): 1.19e-28: 117: 18.59		Q60I23_MOUSE (1102-1308): 2.16e-56: 201: 27.40
+	Hs
		872148 WDR5_HUMAN (208-342): 1.41e-28: 114: 11.85		SOX2_HUMAN (1073-1308): 2.24e-57: 204: 24.05
+	Ce
		1165197 WDR51_CAEEL (57-342): 2.15e-56: 189: 14.14		SOX2_CAEEL (1065-1195): 3.03e-30: 124: 30.53
+	Hs
		142298 PEX7_HUMAN (20-341): 4.04e-59: 194: 17.90		SOX9_HUMAN (1031-1201): 1.05e-24: 112: 23.08
+	Hs
		872374 RBBP7_HUMAN (2-153): 4.87e-15: 77.5: 15.72		SOX2_HUMAN (1073-1308): 2.24e-57: 204: 24.05
+	Mm
		1222087 RBBP7_MOUSE (2-153): 4.28e-15: 77.5: 15.72		Q60I23_MOUSE (1102-1308): 2.16e-56: 201: 27.40
+	Hs
		845363 LIS1_HUMAN (153-340): 1.08e-36: 138: 12.23		SRRM2_HUMAN (850-2517): 1.87e-29: 131: 7.91
+	Hs
		964875 WDR5_HUMAN (208-342): 1.41e-28: 114: 11.85		SRY_HUMAN (1065-1189): 2e-37: 142: 25.60
+	Hs
		1450952 NLE1_HUMAN (249-341): 1.99e-20: 93.7: 15.05		SRRM2_HUMAN (850-2517): 1.87e-29: 131: 7.91
+	Mm
		965395 WDR5_MOUSE (208-342): 1.41e-28: 114: 11.85		KMT2C_MOUSE (744-2499): 9.23e-16: 86.8: 9.17
+	Hs
		1403515 NLE1_HUMAN (249-341): 1.99e-20: 93.7: 15.05		MINT_HUMAN (301-1665): 2.41e-21: 105: 10.27
+	Hs
		1129735 WDR33_HUMAN (7-204): 2.63e-31: 126: 10.61		MDC1_HUMAN (537-1378): 5.47e-10: 67.7: 10.07
+	Hs
		965097 WDR5_HUMAN (208-342): 1.41e-28: 114: 11.85		KMT2C_HUMAN (1133-2516): 1.63e-13: 79.5: 8.66
+	Hs
		1450956 NLE1_HUMAN (249-341): 1.99e-20: 93.7: 15.05		NCOR2_HUMAN (294-2060): 9.59e-17: 89.9: 10.04