HitPredict

Interactor 1: 1433G (P61981)
14-3-3 protein gamma (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein gamma, N-terminally processed]
Gene: YWHAG

Interactor 2: FRMD6 (Q96NE9)
FERM domain-containing protein 6 (Willin)
Gene: FRMD6

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.93	0.60	0.748

Property	Details
Experiments	24366813, 33961781, 36931259, 15324660, 32814053, 17353931, 28514442
Identification Methods	affinity chromatography technology, proximity labelling technology, validated two hybrid, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation, two hybrid array, two hybrid pooling approach, coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0008104 - intracellular protein localization
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 247 Hs			1 622
+	Hs
		971892 1433E_HUMAN (1-244): 2.03e-141: 398: 63.53		FRMD6_HUMAN (1-622): 1.68e-171: 503: 100.00
+	Hs
		971460 1433E_HUMAN (1-244): 2.03e-141: 398: 63.53		PTN13_HUMAN (14-401): 8.53e-120: 394: 24.49
+	Hs
		966254 1433G_HUMAN (1-247): 3.17e-139: 392: 100.00		PTN13_HUMAN (14-401): 8.53e-120: 394: 24.49
+	Hs
		966902 1433G_HUMAN (1-247): 3.17e-139: 392: 100.00		E41L5_HUMAN (5-598): 2.33e-127: 393: 14.73
+	Hs
		708841 1433E_HUMAN (1-244): 2.03e-141: 398: 63.53		PTN4_HUMAN (4-536): 8.73e-120: 379: 14.29
+	Hs
		708840 1433G_HUMAN (1-247): 3.17e-139: 392: 100.00		PTN4_HUMAN (4-536): 8.73e-120: 379: 14.29
+	Hs
		971997 1433E_HUMAN (1-244): 2.03e-141: 398: 63.53		E41L1_HUMAN (18-573): 2.36e-114: 364: 15.00
+	Hs
		972158 1433E_HUMAN (1-244): 2.03e-141: 398: 63.53		E41L3_HUMAN (13-569): 1.1e-111: 361: 13.81
+	Hs
		966871 1433G_HUMAN (1-247): 3.17e-139: 392: 100.00		E41L1_HUMAN (18-573): 2.36e-114: 364: 15.00
+	Hs
		538935 1433E_HUMAN (1-244): 2.03e-141: 398: 63.53		EPB41_HUMAN (14-572): 1.19e-110: 353: 14.83
+	Hs
		538934 1433G_HUMAN (1-247): 3.17e-139: 392: 100.00		EPB41_HUMAN (14-572): 1.19e-110: 353: 14.83
+	Hs
		217418 1433E_HUMAN (1-244): 2.03e-141: 398: 63.53		E41L2_HUMAN (13-545): 1.19e-105: 343: 12.70
+	Hs
		217417 1433G_HUMAN (1-247): 3.17e-139: 392: 100.00		E41L2_HUMAN (13-545): 1.19e-105: 343: 12.70
+	Hs
		683983 1433E_HUMAN (1-244): 2.03e-141: 398: 63.53		PTN3_HUMAN (5-547): 9.84e-102: 331: 14.19
+	Hs
		966540 1433G_HUMAN (1-247): 3.17e-139: 392: 100.00		FRMD5_HUMAN (1-528): 6.02e-107: 335: 19.04
+	Hs
		683982 1433G_HUMAN (1-247): 3.17e-139: 392: 100.00		PTN3_HUMAN (5-547): 9.84e-102: 331: 14.19
+	Mm
		972263 1433E_MOUSE (1-244): 2.03e-141: 398: 63.53		FRM4A_MOUSE (12-334): 6.23e-85: 288: 19.64
+	Mm
		972299 1433E_MOUSE (1-244): 2.03e-141: 398: 63.53		FRM4B_MOUSE (12-379): 1.15e-74: 260: 19.06
+	Hs
		971558 1433E_HUMAN (1-244): 2.03e-141: 398: 63.53		PTN14_HUMAN (20-336): 1.44e-73: 258: 19.75
+	Hs
		966349 1433G_HUMAN (1-247): 3.17e-139: 392: 100.00		PTN14_HUMAN (20-336): 1.44e-73: 258: 19.75