HitPredict

Interactor 1: E9PMD8 (E9PMD8)
Proteasome 26S subunit, ATPase 3
Gene: PSMC3

Interactor 2: PSB2 (P49721)
Proteasome subunit beta type-2 (Macropain subunit C7-I) (Multicatalytic endopeptidase complex subunit C7-I) (Proteasome component C7-I) (Proteasome subunit beta-4) (beta-4)
Gene: PSMB2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.80	0.514

Property	Details
Experiments	35271311
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	AAA~Proteasome
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 301 Hs			1 201
+	Dm
		874969 PRS4_DROME (51-301): 1.41e-87: 270: 40.00		Q7K148_DROME (2-198): 6.1e-66: 205: 22.34
+	Dm
		875020 PRS4_DROME (51-301): 1.41e-87: 270: 40.00		Q9VJJ0_DROME (1-195): 3.55e-66: 203: 51.28
+	Dm
		875036 PRS4_DROME (51-301): 1.41e-87: 270: 40.00		Q9VUJ1_DROME (4-199): 3.14e-64: 201: 19.90
+	Dm
		821820 PRS4_DROME (51-301): 1.41e-87: 270: 40.00		PSA2_DROME (4-197): 4.62e-64: 199: 18.88
+	Hs
		97065 E9PMD8_HUMAN (1-301): 1.06e-81: 250: 100.00		PSB5_HUMAN (2-197): 1.97e-66: 206: 17.86
+	Hs
		97062 E9PMD8_HUMAN (1-301): 1.06e-81: 250: 100.00		PSA4_HUMAN (3-198): 5.78e-65: 202: 17.73
+	Hs
		97083 E9PMD8_HUMAN (1-301): 1.06e-81: 250: 100.00		PSB7_HUMAN (3-199): 1.33e-64: 202: 19.80
+	Hs
		97060 E9PMD8_HUMAN (1-301): 1.06e-81: 250: 100.00		PSA2_HUMAN (4-197): 1.05e-64: 201: 17.86
+	Hs
		610237 PRS6A_HUMAN (20-301): 1.67e-75: 239: 95.47		PSB5_HUMAN (2-197): 1.97e-66: 206: 17.86
+	Hs
		610230 PRS6A_HUMAN (20-301): 1.67e-75: 239: 95.47		PSA4_HUMAN (3-198): 5.78e-65: 202: 17.73
+	Hs
		610445 PRS6A_HUMAN (20-301): 1.67e-75: 239: 95.47		PSB7_HUMAN (3-199): 1.33e-64: 202: 19.80
+	Hs
		610228 PRS6A_HUMAN (20-301): 1.67e-75: 239: 95.47		PSA2_HUMAN (4-197): 1.05e-64: 201: 17.86
+	Hs
		610266 PRS6A_HUMAN (20-301): 1.67e-75: 239: 95.47		PSB2_HUMAN (1-201): 5.43e-65: 200: 100.00
+	Hs
		97058 E9PMD8_HUMAN (1-301): 1.06e-81: 250: 100.00		PSB1_HUMAN (3-198): 2.08e-57: 182: 23.42
+	Hs
		681583 PRS7_HUMAN (14-300): 4.79e-70: 225: 31.36		PSA4_HUMAN (3-198): 5.78e-65: 202: 17.73
+	Hs
		681115 PRS7_HUMAN (14-300): 4.79e-70: 225: 31.36		PSA2_HUMAN (4-197): 1.05e-64: 201: 17.86
+	Hs
		610224 PRS6A_HUMAN (20-301): 1.67e-75: 239: 95.47		PSB1_HUMAN (3-198): 2.08e-57: 182: 23.42
+	Hs
		633613 PRS7_HUMAN (14-300): 4.79e-70: 225: 31.36		PSB1_HUMAN (3-198): 2.08e-57: 182: 23.42
+	Hs
		97064 E9PMD8_HUMAN (1-301): 1.06e-81: 250: 100.00		PSB6_HUMAN (3-188): 2.97e-44: 148: 17.74
+	Hs
		610236 PRS6A_HUMAN (20-301): 1.67e-75: 239: 95.47		PSB6_HUMAN (3-188): 2.97e-44: 148: 17.74