HitPredict

Interactor 1: DYST (Q03001)
Dystonin (230 kDa bullous pemphigoid antigen) (230/240 kDa bullous pemphigoid antigen) (Bullous pemphigoid antigen 1) (BPA) (Bullous pemphigoid antigen) (Dystonia musculorum protein) (Hemidesmosomal plaque protein)
Gene: DST

Interactor 2: MY18A (Q92614)
Unconventional myosin-XVIIIa (Molecule associated with JAK3 N-terminus) (MAJN) (Myosin containing a PDZ domain) (Surfactant protein receptor SP-R210) (SP-R210)
Gene: MYO18A

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	26496610
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	EF-hand_7~Myosin_head, Myosin_head~Spectrin
Common GO terms	GO:0005737 - cytoplasm GO:0016020 - membrane
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 7570 Hs			1 2054
+	Hs
		724786 DYST_HUMAN (1-7570): 0: 2600: 100.00		MYH9_HUMAN (1141-1989): 2.8e-46: 186: 14.96
+	Hs
		963381 SPTB2_HUMAN (5709-7570): 7.99e-22: 108: 12.95		MY18A_HUMAN (1-2054): 0: 1279: 100.00
+	Hs
		164647 SPTN2_HUMAN (5708-7163): 4.91e-17: 92.5: 14.91		MY18A_HUMAN (1-2054): 0: 1279: 100.00
+	Hs
		1045471 SPTN1_HUMAN (269-874): 2.44e-13: 80.3: 13.42		MY18A_HUMAN (1-2054): 0: 1279: 100.00
+	Hs
		1068617 PLEC_HUMAN (1777-1974): 1.7e-12: 77.5: 19.19		MY18A_HUMAN (1-2054): 0: 1279: 100.00
+	Hs
		521484 ACTN1_HUMAN (3770-4283): 1.06e-26: 123: 10.00		MYH9_HUMAN (1141-1989): 2.8e-46: 186: 14.96
+	Hs
		724781 SPTB2_HUMAN (5709-7570): 7.99e-22: 108: 12.95		MYH9_HUMAN (1141-1989): 2.8e-46: 186: 14.96
+	Hs
		725073 MACF1_HUMAN (351-1936): 4.95e-21: 105: 11.05		MYH9_HUMAN (1141-1989): 2.8e-46: 186: 14.96
+	Hs
		164575 SPTN2_HUMAN (5708-7163): 4.91e-17: 92.5: 14.91		MYH9_HUMAN (1141-1989): 2.8e-46: 186: 14.96
+	Hs
		110636 H3BPE1_HUMAN (274-1767): 5.34e-16: 89.4: 9.72		MYH9_HUMAN (1141-1989): 2.8e-46: 186: 14.96
+	Mm
		93570 DESP_MOUSE (1555-1738): 6.77e-09: 65.9: 27.57		MYH9_MOUSE (1173-2014): 1.03e-51: 204: 16.16
+	Hs
		724817 SPTN1_HUMAN (269-874): 2.44e-13: 80.3: 13.42		MYH9_HUMAN (1141-1989): 2.8e-46: 186: 14.96
+	Hs
		724839 PLEC_HUMAN (1777-1974): 1.7e-12: 77.5: 19.19		MYH9_HUMAN (1141-1989): 2.8e-46: 186: 14.96
+	Hs
		522612 SPTN1_HUMAN (269-874): 2.44e-13: 80.3: 13.42		MYH7_HUMAN (954-1819): 2.95e-41: 169: 12.80
+	Hs
		1068591 PLEC_HUMAN (1777-1974): 1.7e-12: 77.5: 19.19		MY18B_HUMAN (1024-1700): 3.43e-34: 146: 11.13
+	Hs
		963431 SPTB2_HUMAN (5709-7570): 7.99e-22: 108: 12.95		MYO5C_HUMAN (1119-1615): 4.36e-24: 113: 12.21
+	Hs
		1045537 SPTN1_HUMAN (269-874): 2.44e-13: 80.3: 13.42		MYO5C_HUMAN (1119-1615): 4.36e-24: 113: 12.21
+	Dm
		404218 ACTN_DROME (3594-4062): 2.01e-11: 73.6: 9.98		MYSA_DROME (1659-2054): 1.99e-22: 108: 12.50